diff --git a/dkist/dataset/tiled_dataset.py b/dkist/dataset/tiled_dataset.py
index 08a85780..5f7fe3e9 100644
--- a/dkist/dataset/tiled_dataset.py
+++ b/dkist/dataset/tiled_dataset.py
@@ -118,7 +118,7 @@ def __getitem__(self, aslice):
 
     @staticmethod
     def _validate_component_datasets(datasets, inventory):
-        datasets = datasets.compressed()
+        datasets = [ds for ds in datasets.compressed() if ds is not None]
         inv_1 = datasets[0].meta["inventory"]
         if inv_1 and inv_1 is not inventory:
             raise ValueError("The inventory record of the first dataset does not match the one passed to TiledDataset")