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DESCRIPTION
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DESCRIPTION
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Package: MERINGUE
Title: Characterizing spatial gene expression heterogeneity in spatially resolved single-cell transcriptomics data with non-uniform cellular densities
Version: 1.0
Authors@R: person("Jean", "Fan",
email = "[email protected]", role = c("aut", "cre"),
comment = c(ORCID = "0000-0002-0212-5451"))
Description: MERINGUE is a computational framework based on spatial auto-correlation and cross-correlation analysis to identify genes with spatially heterogeneous expression patterns, derive putative cell-cell communication, and perform spatially informed cell clustering in 2D and 3D in a density-agnostic manner using spatially resolved transcriptomics data.
Depends: R (>= 3.0.0)
License: GPL-3 + file LICENSE
Encoding: UTF-8
LazyData: true
Imports:
RANN,
Matrix,
akima,
Rcpp,
dynamicTreeCut,
geometry,
DT,
igraph,
mgcv,
clue
LinkingTo: Rcpp, RcppArmadillo, RcppProgress
RoxygenNote: 7.1.1
Suggests:
knitr,
markdown,
rmarkdown,
testthat,
rcmdcheck,
shiny,
Rtsne,
uwot,
rgl
VignetteBuilder: knitr