diff --git a/src/llvm-late-gc-lowering.cpp b/src/llvm-late-gc-lowering.cpp
index a48fd1a96eb8fc..642c828280d50f 100644
--- a/src/llvm-late-gc-lowering.cpp
+++ b/src/llvm-late-gc-lowering.cpp
@@ -729,7 +729,7 @@ void LateLowerGCFrame::NoteUse(State &S, BBState &BBS, Value *V, BitVector &Uses
 void LateLowerGCFrame::NoteOperandUses(State &S, BBState &BBS, User &UI, BitVector &Uses) {
     for (Use &U : UI.operands()) {
         Value *V = U;
-        if (!isSpecialPtr(V->getType()))
+        if (!isSpecialPtr(V->getType()) && !isSpecialPtrVec(V->getType()))
             continue;
         NoteUse(S, BBS, V, Uses);
     }
diff --git a/test/core.jl b/test/core.jl
index f9a08f1a990bfc..d843c2dbe1e902 100644
--- a/test/core.jl
+++ b/test/core.jl
@@ -6675,3 +6675,23 @@ c28399 = 42
 @test g28399(0)() == 42
 @test g28399(1)() == 42
 @test_throws UndefVarError(:__undef_28399__) f28399()
+
+# issue #28445
+mutable struct foo28445
+    x::Int
+end
+
+@noinline make_foo28445() = (foo28445(1), foo28445(rand(1:10)), foo28445(rand(1:10)))
+@noinline function use_tuple28445(c)
+	@test isa(c[2], foo28445)
+    @test isa(c[3], foo28445)
+end
+
+function repackage28445()
+    (_, a, b) = make_foo28445()
+    GC.gc()
+    c = (foo28445(1), foo28445(2), a, b)
+    use_tuple28445(c)
+    true
+end
+@test repackage28445()
diff --git a/test/llvmpasses/gcroots.ll b/test/llvmpasses/gcroots.ll
index 25d75a8a7a0d16..958a735b8efcab 100644
--- a/test/llvmpasses/gcroots.ll
+++ b/test/llvmpasses/gcroots.ll
@@ -401,6 +401,19 @@ top:
    ret i8 %val
 }
 
+define %jl_value_t addrspace(10)* @vecstoreload(<2 x %jl_value_t addrspace(10)*> *%arg) {
+; CHECK-LABEL: @vecstoreload
+; CHECK: %gcframe = alloca %jl_value_t addrspace(10)*, i32 4
+top:
+    %ptls = call %jl_value_t*** @julia.ptls_states()
+    %loaded = load <2 x %jl_value_t addrspace(10)*>, <2 x %jl_value_t addrspace(10)*> *%arg
+    call void @jl_safepoint()
+    %obj = call %jl_value_t addrspace(10) *@alloc()
+    %casted = bitcast %jl_value_t addrspace(10)* %obj to <2 x %jl_value_t addrspace(10)*> addrspace(10)*
+    store <2 x %jl_value_t addrspace(10)*> %loaded, <2 x %jl_value_t addrspace(10)*> addrspace(10)* %casted
+    ret %jl_value_t addrspace(10)* %obj
+}
+
 !0 = !{!"jtbaa"}
 !1 = !{!"jtbaa_const", !0, i64 0}
 !2 = !{!1, !1, i64 0, i64 1}