diff --git a/benchmarks/py-naarad/Makefile b/benchmarks/py-naarad/Makefile
index c5c3287450a8..a880d69eb036 100644
--- a/benchmarks/py-naarad/Makefile
+++ b/benchmarks/py-naarad/Makefile
@@ -12,8 +12,7 @@ COMMENT=	Framework for performance analysis
 LICENSE=	APACHE20
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}argparse>0:devel/py-argparse \
-	${PYTHON_PKGNAMEPREFIX}pytz>=2013.8,1:devel/py-pytz \
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pytz>=2013.8,1:devel/py-pytz \
 	${PYTHON_PKGNAMEPREFIX}Jinja2>0:devel/py-Jinja2 \
 	${PYTHON_PKGNAMEPREFIX}luminol>0:math/py-luminol \
 	bash:shells/bash \
diff --git a/devel/py-numba/Makefile b/devel/py-numba/Makefile
index 32c0cc996695..b07d72b37d15 100644
--- a/devel/py-numba/Makefile
+++ b/devel/py-numba/Makefile
@@ -14,8 +14,7 @@ LICENSE=	BSD
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
 BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}numpy>1.7,1:math/py-numpy
-RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}llvmlite>=0.12:devel/py-llvmlite \
-		${PYTHON_PKGNAMEPREFIX}argparse>0:devel/py-argparse
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}llvmlite>=0.12:devel/py-llvmlite
 
 # Uses Python 2.7, 3.4+
 USES=		python fortran
diff --git a/net/cloud-init/Makefile b/net/cloud-init/Makefile
index 2aa4d2a58239..e63a72ae9840 100644
--- a/net/cloud-init/Makefile
+++ b/net/cloud-init/Makefile
@@ -20,7 +20,6 @@ RUN_DEPENDS=	dmidecode>0:sysutils/dmidecode \
 		${PYTHON_PKGNAMEPREFIX}prettytable>0:devel/py-prettytable \
 		${PYTHON_PKGNAMEPREFIX}configobj>0:devel/py-configobj \
 		${PYTHON_PKGNAMEPREFIX}yaml>0:devel/py-yaml \
-		${PYTHON_PKGNAMEPREFIX}argparse>0:devel/py-argparse \
 		${PYTHON_PKGNAMEPREFIX}six>0:devel/py-six \
 		${PYTHON_PKGNAMEPREFIX}serial>0:comms/py-serial \
 		${PYTHON_PKGNAMEPREFIX}requests>0:www/py-requests \
diff --git a/net/py-magic-wormhole/Makefile b/net/py-magic-wormhole/Makefile
index 94ab01d2c652..4e9720d8e655 100644
--- a/net/py-magic-wormhole/Makefile
+++ b/net/py-magic-wormhole/Makefile
@@ -12,7 +12,6 @@ COMMENT=	Get things from one computer to another, safely
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}tqdm>0:misc/py-tqdm \
 		${PYTHON_PKGNAMEPREFIX}hkdf>0:security/py-hkdf \
 		${PYTHON_PKGNAMEPREFIX}autobahn>=0.14.1:www/py-autobahn \
-		${PYTHON_PKGNAMEPREFIX}argparse>0:devel/py-argparse \
 		${PYTHON_PKGNAMEPREFIX}pynacl>=0.3.0:security/py-pynacl \
 		${PYTHON_PKGNAMEPREFIX}spake2>=0.7:security/py-spake2 \
 		${PYTHON_PKGNAMEPREFIX}txaio>=2.5.1:devel/py-txaio
diff --git a/print/cloudprint/Makefile b/print/cloudprint/Makefile
index dead64999591..9ceefd0c3535 100644
--- a/print/cloudprint/Makefile
+++ b/print/cloudprint/Makefile
@@ -13,7 +13,6 @@ LICENSE=	GPLv3
 
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pycups>=0:print/py-pycups \
 		${PYTHON_PKGNAMEPREFIX}daemon>0:devel/py-daemon \
-		${PYTHON_PKGNAMEPREFIX}argparse>=0:devel/py-argparse \
 		${PYTHON_PKGNAMEPREFIX}requests>=2.7.0:www/py-requests
 
 USE_GITHUB=	yes
diff --git a/security/obfsproxy/Makefile b/security/obfsproxy/Makefile
index ac74f4a36efc..5413a311adeb 100644
--- a/security/obfsproxy/Makefile
+++ b/security/obfsproxy/Makefile
@@ -13,7 +13,6 @@ COMMENT=	Pluggable transport proxy
 LICENSE=	BSD3CLAUSE
 
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pyptlib>=0.0.5:security/py-pyptlib \
-		${PYTHON_PKGNAMEPREFIX}argparse>0:devel/py-argparse \
 		${PYTHON_PKGNAMEPREFIX}pycrypto>=2.1:security/py-pycrypto \
 		${PYTHON_PKGNAMEPREFIX}yaml>=0:devel/py-yaml
 
diff --git a/sysutils/osquery/Makefile b/sysutils/osquery/Makefile
index cabed861c02b..1cc1b8a72c6a 100644
--- a/sysutils/osquery/Makefile
+++ b/sysutils/osquery/Makefile
@@ -20,7 +20,6 @@ BUILD_DEPENDS=	snappy>0:archivers/snappy \
 		doxygen:devel/doxygen \
 		${PYTHON_PKGNAMEPREFIX}MarkupSafe>0:textproc/py-MarkupSafe \
 		${PYTHON_PKGNAMEPREFIX}psutil>0:sysutils/py-psutil \
-		${PYTHON_PKGNAMEPREFIX}argparse>0:devel/py-argparse \
 		${PYTHON_PKGNAMEPREFIX}pexpect>0:misc/py-pexpect \
 		${PYTHON_PKGNAMEPREFIX}Jinja2>0:devel/py-Jinja2  \
 		${PYTHON_PKGNAMEPREFIX}thrift>0:devel/py-thrift \
diff --git a/www/py-cactus/Makefile b/www/py-cactus/Makefile
index d1305cbd06c8..4a555ae70b96 100644
--- a/www/py-cactus/Makefile
+++ b/www/py-cactus/Makefile
@@ -15,7 +15,6 @@ LICENSE=	BSD3CLAUSE
 
 RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}django16>0:www/py-django16 \
 		${PYTHON_PKGNAMEPREFIX}markdown2>0:textproc/py-markdown2 \
-		${PYTHON_PKGNAMEPREFIX}argparse>0:devel/py-argparse \
 		${PYTHON_PKGNAMEPREFIX}boto>=2.4.1:devel/py-boto \
 		${PYTHON_PKGNAMEPREFIX}tornado>=3.2:www/py-tornado \
 		${PYTHON_PKGNAMEPREFIX}colorlog>0:devel/py-colorlog \