diff --git a/pkgs/development/ocaml-modules/hxd/default.nix b/pkgs/development/ocaml-modules/hxd/default.nix
index d3a8ce7a85bd2..de60667327b41 100644
--- a/pkgs/development/ocaml-modules/hxd/default.nix
+++ b/pkgs/development/ocaml-modules/hxd/default.nix
@@ -23,6 +23,10 @@ buildDunePackage rec {
 
   doCheck = true;
 
+  preCheck = ''
+    export DUNE_CACHE=disabled
+  '';
+
   meta = with lib; {
     description = "Hexdump in OCaml";
     homepage = "https://github.com/dinosaure/hxd";
diff --git a/pkgs/development/ocaml-modules/ocplib-simplex/default.nix b/pkgs/development/ocaml-modules/ocplib-simplex/default.nix
index 74ca96b18661f..7d1c2d49d7781 100644
--- a/pkgs/development/ocaml-modules/ocplib-simplex/default.nix
+++ b/pkgs/development/ocaml-modules/ocplib-simplex/default.nix
@@ -1,4 +1,4 @@
-{ lib, fetchFromGitHub, buildDunePackage, logs, zarith }:
+{ lib, fetchFromGitHub, fetchpatch, buildDunePackage, logs, zarith }:
 
 buildDunePackage rec {
   pname = "ocplib-simplex";
@@ -11,6 +11,13 @@ buildDunePackage rec {
     hash = "sha256-fLTht+TlyJIsIAsRLmmkFKsnbSeW3BgyAyURFdnGfko=";
   };
 
+  # Fix tests with dune 3.17.0
+  # See https://github.com/OCamlPro/ocplib-simplex/issues/35
+  patches = (fetchpatch {
+    url = "https://github.com/OCamlPro/ocplib-simplex/commit/456a744bddd397daade7959d4a49cfadafdadd33.patch";
+    hash = "sha256-tQUXOoRGe1AIzHcm6j2MopROxn75OE9YUP+CwcKUbVg=";
+  });
+
   propagatedBuildInputs = [ logs zarith ];
 
   doCheck = true;
diff --git a/pkgs/development/ocaml-modules/reason-react/default.nix b/pkgs/development/ocaml-modules/reason-react/default.nix
index 340b0c1c27b13..a447c3172d60b 100644
--- a/pkgs/development/ocaml-modules/reason-react/default.nix
+++ b/pkgs/development/ocaml-modules/reason-react/default.nix
@@ -17,6 +17,11 @@ buildDunePackage {
     melange
   ];
   doCheck = true;
+  # Fix tests with dune 3.17.0
+  # See https://github.com/reasonml/reason-react/issues/870
+  preCheck = ''
+    export DUNE_CACHE=disabled
+  '';
   meta = reason-react-ppx.meta // {
     description = "Reason bindings for React.js";
   };
diff --git a/pkgs/development/tools/ocaml/dune/3.nix b/pkgs/development/tools/ocaml/dune/3.nix
index 289f81af57023..0cadd4fb20e06 100644
--- a/pkgs/development/tools/ocaml/dune/3.nix
+++ b/pkgs/development/tools/ocaml/dune/3.nix
@@ -6,11 +6,11 @@ else
 
 stdenv.mkDerivation rec {
   pname = "dune";
-  version = "3.16.1";
+  version = "3.17.0";
 
   src = fetchurl {
     url = "https://github.com/ocaml/dune/releases/download/${version}/dune-${version}.tbz";
-    hash = "sha256-t4GuIPh2E8KhG9BxeAngBHDILWFeFSZPmmTgMwUaw94=";
+    hash = "sha256-LDqmxB7Tnj1sGiktdfSAa9gDEIQa/FFnOqWc6cgWUHw=";
   };
 
   nativeBuildInputs = [ ocaml findlib ];