diff --git a/src/main/java/io/reactivex/internal/operators/flowable/FlowableCombineLatest.java b/src/main/java/io/reactivex/internal/operators/flowable/FlowableCombineLatest.java
index 30c9443319..07f7e8e7d4 100644
--- a/src/main/java/io/reactivex/internal/operators/flowable/FlowableCombineLatest.java
+++ b/src/main/java/io/reactivex/internal/operators/flowable/FlowableCombineLatest.java
@@ -16,6 +16,7 @@
 import java.util.Iterator;
 import java.util.concurrent.atomic.*;
 
+import io.reactivex.annotations.NonNull;
 import io.reactivex.annotations.Nullable;
 import org.reactivestreams.*;
 
@@ -37,8 +38,10 @@
 public final class FlowableCombineLatest<T, R>
 extends Flowable<R> {
 
+    @Nullable
     final Publisher<? extends T>[] array;
 
+    @Nullable
     final Iterable<? extends Publisher<? extends T>> iterable;
 
     final Function<? super Object[], ? extends R> combiner;
@@ -47,8 +50,8 @@ public final class FlowableCombineLatest<T, R>
 
     final boolean delayErrors;
 
-    public FlowableCombineLatest(Publisher<? extends T>[] array,
-            Function<? super Object[], ? extends R> combiner,
+    public FlowableCombineLatest(@NonNull Publisher<? extends T>[] array,
+                    @NonNull Function<? super Object[], ? extends R> combiner,
                     int bufferSize, boolean delayErrors) {
         this.array = array;
         this.iterable = null;
@@ -57,8 +60,8 @@ public FlowableCombineLatest(Publisher<? extends T>[] array,
         this.delayErrors = delayErrors;
     }
 
-    public FlowableCombineLatest(Iterable<? extends Publisher<? extends T>> iterable,
-            Function<? super Object[], ? extends R> combiner,
+    public FlowableCombineLatest(@NonNull Iterable<? extends Publisher<? extends T>> iterable,
+                    @NonNull Function<? super Object[], ? extends R> combiner,
                     int bufferSize, boolean delayErrors) {
         this.array = null;
         this.iterable = iterable;
diff --git a/src/main/java/io/reactivex/internal/operators/flowable/FlowableWithLatestFromMany.java b/src/main/java/io/reactivex/internal/operators/flowable/FlowableWithLatestFromMany.java
index 629a50a4ac..e130c7e775 100644
--- a/src/main/java/io/reactivex/internal/operators/flowable/FlowableWithLatestFromMany.java
+++ b/src/main/java/io/reactivex/internal/operators/flowable/FlowableWithLatestFromMany.java
@@ -15,6 +15,8 @@
 import java.util.Arrays;
 import java.util.concurrent.atomic.*;
 
+import io.reactivex.annotations.NonNull;
+import io.reactivex.annotations.Nullable;
 import org.reactivestreams.*;
 
 import io.reactivex.disposables.Disposable;
@@ -33,21 +35,22 @@
  * @param <R> the output type
  */
 public final class FlowableWithLatestFromMany<T, R> extends AbstractFlowableWithUpstream<T, R> {
-
+    @Nullable
     final Publisher<?>[] otherArray;
 
+    @Nullable
     final Iterable<? extends Publisher<?>> otherIterable;
 
     final Function<? super Object[], R> combiner;
 
-    public FlowableWithLatestFromMany(Publisher<T> source, Publisher<?>[] otherArray, Function<? super Object[], R> combiner) {
+    public FlowableWithLatestFromMany(@NonNull Publisher<T> source, @NonNull Publisher<?>[] otherArray, Function<? super Object[], R> combiner) {
         super(source);
         this.otherArray = otherArray;
         this.otherIterable = null;
         this.combiner = combiner;
     }
 
-    public FlowableWithLatestFromMany(Publisher<T> source, Iterable<? extends Publisher<?>> otherIterable, Function<? super Object[], R> combiner) {
+    public FlowableWithLatestFromMany(@NonNull Publisher<T> source, @NonNull Iterable<? extends Publisher<?>> otherIterable, @NonNull Function<? super Object[], R> combiner) {
         super(source);
         this.otherArray = null;
         this.otherIterable = otherIterable;
diff --git a/src/main/java/io/reactivex/internal/operators/maybe/MaybeFlatMapIterableObservable.java b/src/main/java/io/reactivex/internal/operators/maybe/MaybeFlatMapIterableObservable.java
index af3027ca00..21cee4e184 100644
--- a/src/main/java/io/reactivex/internal/operators/maybe/MaybeFlatMapIterableObservable.java
+++ b/src/main/java/io/reactivex/internal/operators/maybe/MaybeFlatMapIterableObservable.java
@@ -101,7 +101,7 @@ public void onSuccess(T value) {
 
             this.it = iter;
 
-            if (outputFused && iter != null) {
+            if (outputFused) {
                 a.onNext(null);
                 a.onComplete();
                 return;
diff --git a/src/main/java/io/reactivex/internal/operators/observable/ObservableWithLatestFromMany.java b/src/main/java/io/reactivex/internal/operators/observable/ObservableWithLatestFromMany.java
index 21d5c8f975..dd58b0123f 100644
--- a/src/main/java/io/reactivex/internal/operators/observable/ObservableWithLatestFromMany.java
+++ b/src/main/java/io/reactivex/internal/operators/observable/ObservableWithLatestFromMany.java
@@ -16,6 +16,8 @@
 import java.util.concurrent.atomic.*;
 
 import io.reactivex.*;
+import io.reactivex.annotations.NonNull;
+import io.reactivex.annotations.Nullable;
 import io.reactivex.disposables.Disposable;
 import io.reactivex.exceptions.Exceptions;
 import io.reactivex.functions.Function;
@@ -33,20 +35,23 @@
  */
 public final class ObservableWithLatestFromMany<T, R> extends AbstractObservableWithUpstream<T, R> {
 
+    @Nullable
     final ObservableSource<?>[] otherArray;
 
+    @Nullable
     final Iterable<? extends ObservableSource<?>> otherIterable;
 
+    @NonNull
     final Function<? super Object[], R> combiner;
 
-    public ObservableWithLatestFromMany(ObservableSource<T> source, ObservableSource<?>[] otherArray, Function<? super Object[], R> combiner) {
+    public ObservableWithLatestFromMany(@NonNull ObservableSource<T> source, @NonNull ObservableSource<?>[] otherArray, @NonNull Function<? super Object[], R> combiner) {
         super(source);
         this.otherArray = otherArray;
         this.otherIterable = null;
         this.combiner = combiner;
     }
 
-    public ObservableWithLatestFromMany(ObservableSource<T> source, Iterable<? extends ObservableSource<?>> otherIterable, Function<? super Object[], R> combiner) {
+    public ObservableWithLatestFromMany(@NonNull ObservableSource<T> source, @NonNull Iterable<? extends ObservableSource<?>> otherIterable, @NonNull Function<? super Object[], R> combiner) {
         super(source);
         this.otherArray = null;
         this.otherIterable = otherIterable;
diff --git a/src/main/java/io/reactivex/internal/schedulers/ComputationScheduler.java b/src/main/java/io/reactivex/internal/schedulers/ComputationScheduler.java
index 5faaa555a5..f2a4dcf7d3 100644
--- a/src/main/java/io/reactivex/internal/schedulers/ComputationScheduler.java
+++ b/src/main/java/io/reactivex/internal/schedulers/ComputationScheduler.java
@@ -199,7 +199,7 @@ public Disposable schedule(@NonNull Runnable action) {
                 return EmptyDisposable.INSTANCE;
             }
 
-            return poolWorker.scheduleActual(action, 0, null, serial);
+            return poolWorker.scheduleActual(action, 0, TimeUnit.MILLISECONDS, serial);
         }
         @NonNull
         @Override
diff --git a/src/main/java/io/reactivex/internal/schedulers/NewThreadWorker.java b/src/main/java/io/reactivex/internal/schedulers/NewThreadWorker.java
index ea45d78e60..12f121135b 100644
--- a/src/main/java/io/reactivex/internal/schedulers/NewThreadWorker.java
+++ b/src/main/java/io/reactivex/internal/schedulers/NewThreadWorker.java
@@ -17,6 +17,7 @@
 
 import io.reactivex.Scheduler;
 import io.reactivex.annotations.NonNull;
+import io.reactivex.annotations.Nullable;
 import io.reactivex.disposables.*;
 import io.reactivex.internal.disposables.*;
 import io.reactivex.plugins.RxJavaPlugins;
@@ -106,7 +107,8 @@ public Disposable schedulePeriodicallyDirect(final Runnable run, long initialDel
      * @param parent the optional tracker parent to add the created ScheduledRunnable instance to before it gets scheduled
      * @return the ScheduledRunnable instance
      */
-    public ScheduledRunnable scheduleActual(final Runnable run, long delayTime, TimeUnit unit, DisposableContainer parent) {
+    @NonNull
+    public ScheduledRunnable scheduleActual(final Runnable run, long delayTime, @NonNull TimeUnit unit, @Nullable DisposableContainer parent) {
         Runnable decoratedRun = RxJavaPlugins.onSchedule(run);
 
         ScheduledRunnable sr = new ScheduledRunnable(decoratedRun, parent);
@@ -126,7 +128,9 @@ public ScheduledRunnable scheduleActual(final Runnable run, long delayTime, Time
             }
             sr.setFuture(f);
         } catch (RejectedExecutionException ex) {
-            parent.remove(sr);
+            if (parent != null) {
+                parent.remove(sr);
+            }
             RxJavaPlugins.onError(ex);
         }
 
diff --git a/src/test/java/io/reactivex/schedulers/NewThreadSchedulerTest.java b/src/test/java/io/reactivex/schedulers/NewThreadSchedulerTest.java
index 74cf9e181c..0fde9e592b 100644
--- a/src/test/java/io/reactivex/schedulers/NewThreadSchedulerTest.java
+++ b/src/test/java/io/reactivex/schedulers/NewThreadSchedulerTest.java
@@ -115,4 +115,22 @@ public void run() {
 
         assertEquals(0, calls[0]);
     }
+
+    /**
+     * Regression test to ensure there is no NPE when the worker has been disposed
+     */
+    @Test
+    public void npeRegression() throws Exception {
+        Scheduler s = getScheduler();
+        NewThreadWorker w = (NewThreadWorker) s.createWorker();
+        w.dispose();
+
+        //This method used to throw a NPE when the worker has been disposed and the parent is null
+        w.scheduleActual(new Runnable() {
+            @Override
+            public void run() {
+            }
+        }, 0, TimeUnit.MILLISECONDS, null);
+
+    }
 }