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DESCRIPTION
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Package: methyLImp2
Title: Missing value estimation of DNA methylation data
Version: 1.1.1
Authors@R: c(
person("Pietro", "Di Lena",
role = c("aut"),
comment = c(ORCID = "0000-0002-1838-8918")),
person("Anna", "Plaksienko",
email = "[email protected]",
role = c("aut", "cre"),
comment = c(ORCID = "0000-0001-9607-057X")),
person("Claudia", "Angelini",
role = c("aut"),
comment = c(ORCID = "0000-0001-8350-8464")),
person("Christine", "Nardini",
role = c("aut"),
comment = c(ORCID = "0000-0001-7601-321X")))
Description: This package allows to estimate missing values in DNA methylation data. methyLImp method is based on linear regression since methylation levels show a high degree of inter-sample correlation. Implementation is parallelised over chromosomes since probes on different chromosomes are usually independent. Mini-batch approach to reduce the runtime in case of large number of samples is available.
Imports: BiocParallel, parallel, stats, methods, corpcor, SummarizedExperiment, utils
Depends: R (>= 4.3.0), ChAMPdata
URL: https://github.com/annaplaksienko/methyLImp2
BugReports: https://github.com/annaplaksienko/methyLImp2/issues
License: GPL-3
Encoding: UTF-8
RoxygenNote: 7.3.1
biocViews: DNAMethylation, Microarray, Software, MethylationArray, Regression
Suggests:
BiocStyle,
knitr,
rmarkdown,
spelling,
testthat (>= 3.0.0)
VignetteBuilder: knitr
Config/testthat/edition: 3
Language: en-US