diff --git a/crates/uv-python/src/discovery.rs b/crates/uv-python/src/discovery.rs
index a71709254451..84ba940b3fc3 100644
--- a/crates/uv-python/src/discovery.rs
+++ b/crates/uv-python/src/discovery.rs
@@ -776,12 +776,32 @@ pub fn find_python_installations<'a>(
                     .map(FindPythonResult::Ok)
             })
         }),
-        PythonRequest::Version(version) => Box::new({
-            debug!("Searching for {request} in {preference}");
-            python_interpreters(Some(version), None, environments, preference, cache)
+        PythonRequest::Version(version) => {
+            if let Err(err) = version.check_supported() {
+                return Box::new(std::iter::once(Err(Error::InvalidVersionRequest(err))));
+            };
+            Box::new({
+                debug!("Searching for {request} in {preference}");
+                python_interpreters(Some(version), None, environments, preference, cache)
+                    .filter(|result| match result {
+                        Err(_) => true,
+                        Ok((_source, interpreter)) => version.matches_interpreter(interpreter),
+                    })
+                    .map(|result| {
+                        result
+                            .map(PythonInstallation::from_tuple)
+                            .map(FindPythonResult::Ok)
+                    })
+            })
+        }
+        PythonRequest::Implementation(implementation) => Box::new({
+            debug!("Searching for a {request} interpreter in {preference}");
+            python_interpreters(None, Some(implementation), environments, preference, cache)
                 .filter(|result| match result {
                     Err(_) => true,
-                    Ok((_source, interpreter)) => version.matches_interpreter(interpreter),
+                    Ok((_source, interpreter)) => interpreter
+                        .implementation_name()
+                        .eq_ignore_ascii_case(implementation.into()),
                 })
                 .map(|result| {
                     result
@@ -789,64 +809,61 @@ pub fn find_python_installations<'a>(
                         .map(FindPythonResult::Ok)
                 })
         }),
-        PythonRequest::Implementation(implementation) => Box::new({
-            debug!("Searching for a {request} interpreter in {preference}");
-            python_interpreters(None, Some(implementation), environments, preference, cache)
+        PythonRequest::ImplementationVersion(implementation, version) => {
+            if let Err(err) = version.check_supported() {
+                return Box::new(std::iter::once(Err(Error::InvalidVersionRequest(err))));
+            };
+            Box::new({
+                debug!("Searching for {request} in {preference}");
+                python_interpreters(
+                    Some(version),
+                    Some(implementation),
+                    environments,
+                    preference,
+                    cache,
+                )
                 .filter(|result| match result {
                     Err(_) => true,
-                    Ok((_source, interpreter)) => interpreter
-                        .implementation_name()
-                        .eq_ignore_ascii_case(implementation.into()),
+                    Ok((_source, interpreter)) => {
+                        version.matches_interpreter(interpreter)
+                            && interpreter
+                                .implementation_name()
+                                .eq_ignore_ascii_case(implementation.into())
+                    }
                 })
                 .map(|result| {
                     result
                         .map(PythonInstallation::from_tuple)
                         .map(FindPythonResult::Ok)
                 })
-        }),
-        PythonRequest::ImplementationVersion(implementation, version) => Box::new({
-            debug!("Searching for {request} in {preference}");
-            python_interpreters(
-                Some(version),
-                Some(implementation),
-                environments,
-                preference,
-                cache,
-            )
-            .filter(|result| match result {
-                Err(_) => true,
-                Ok((_source, interpreter)) => {
-                    version.matches_interpreter(interpreter)
-                        && interpreter
-                            .implementation_name()
-                            .eq_ignore_ascii_case(implementation.into())
-                }
-            })
-            .map(|result| {
-                result
-                    .map(PythonInstallation::from_tuple)
-                    .map(FindPythonResult::Ok)
-            })
-        }),
-        PythonRequest::Key(request) => Box::new({
-            debug!("Searching for {request} in {preference}");
-            python_interpreters(
-                request.version(),
-                request.implementation(),
-                environments,
-                preference,
-                cache,
-            )
-            .filter(|result| match result {
-                Err(_) => true,
-                Ok((_source, interpreter)) => request.satisfied_by_interpreter(interpreter),
             })
-            .map(|result| {
-                result
-                    .map(PythonInstallation::from_tuple)
-                    .map(FindPythonResult::Ok)
+        }
+        PythonRequest::Key(request) => {
+            if let Some(version) = request.version() {
+                if let Err(err) = version.check_supported() {
+                    return Box::new(std::iter::once(Err(Error::InvalidVersionRequest(err))));
+                };
+            };
+            Box::new({
+                debug!("Searching for {request} in {preference}");
+                python_interpreters(
+                    request.version(),
+                    request.implementation(),
+                    environments,
+                    preference,
+                    cache,
+                )
+                .filter(|result| match result {
+                    Err(_) => true,
+                    Ok((_source, interpreter)) => request.satisfied_by_interpreter(interpreter),
+                })
+                .map(|result| {
+                    result
+                        .map(PythonInstallation::from_tuple)
+                        .map(FindPythonResult::Ok)
+                })
             })
-        }),
+        }
     }
 }
 
@@ -1446,6 +1463,37 @@ impl VersionRequest {
             .flatten()
     }
 
+    pub(crate) fn check_supported(&self) -> Result<(), String> {
+        match self {
+            Self::Any => (),
+            Self::Major(major) => {
+                if *major < 3 {
+                    return Err(format!(
+                        "Python <3 is not supported but {major} was requested."
+                    ));
+                }
+            }
+            Self::MajorMinor(major, minor) => {
+                if (*major, *minor) < (3, 7) {
+                    return Err(format!(
+                        "Python <3.7 is not supported but {major}.{minor} was requested."
+                    ));
+                }
+            }
+            Self::MajorMinorPatch(major, minor, patch) => {
+                if (*major, *minor) < (3, 7) {
+                    return Err(format!(
+                        "Python <3.7 is not supported but {major}.{minor}.{patch} was requested."
+                    ));
+                }
+            }
+            // TODO(zanieb): We could do some checking here to see if the range can be satisfied
+            Self::Range(_) => (),
+        }
+
+        Ok(())
+    }
+
     /// Check if a interpreter matches the requested Python version.
     pub(crate) fn matches_interpreter(&self, interpreter: &Interpreter) -> bool {
         match self {
diff --git a/crates/uv/tests/python_find.rs b/crates/uv/tests/python_find.rs
index bafdb9fd658b..1021f9f60364 100644
--- a/crates/uv/tests/python_find.rs
+++ b/crates/uv/tests/python_find.rs
@@ -403,7 +403,17 @@ fn python_find_unsupported_version() {
     ----- stdout -----
 
     ----- stderr -----
-    error: No interpreter found for Python 3.6 in virtual environments or system path
+    error: Invalid version request: Python <3.7 is not supported but 3.6 was requested.
+    "###);
+
+    // Request a low version with a patch
+    uv_snapshot!(context.filters(), context.python_find().arg("3.6.9"), @r###"
+    success: false
+    exit_code: 2
+    ----- stdout -----
+
+    ----- stderr -----
+    error: Invalid version request: Python <3.7 is not supported but 3.6.9 was requested.
     "###);
 
     // Request a really low version
@@ -413,7 +423,17 @@ fn python_find_unsupported_version() {
     ----- stdout -----
 
     ----- stderr -----
-    error: No interpreter found for Python 2.6 in virtual environments or system path
+    error: Invalid version request: Python <3.7 is not supported but 2.6 was requested.
+    "###);
+
+    // Request a really low version with a patch
+    uv_snapshot!(context.filters(), context.python_find().arg("2.6.8"), @r###"
+    success: false
+    exit_code: 2
+    ----- stdout -----
+
+    ----- stderr -----
+    error: Invalid version request: Python <3.7 is not supported but 2.6.8 was requested.
     "###);
 
     // Request a future version
@@ -425,4 +445,14 @@ fn python_find_unsupported_version() {
     ----- stderr -----
     error: No interpreter found for Python 4.2 in virtual environments or system path
     "###);
+
+    // Request a low version with a range
+    uv_snapshot!(context.filters(), context.python_find().arg("<3.0"), @r###"
+    success: false
+    exit_code: 2
+    ----- stdout -----
+
+    ----- stderr -----
+    error: No interpreter found for Python <3.0 in virtual environments or system path
+    "###);
 }