diff --git a/tests/test_bugs.py b/tests/test_bugs.py
index 2103b98..6ffeb22 100644
--- a/tests/test_bugs.py
+++ b/tests/test_bugs.py
@@ -17,6 +17,8 @@
 # CONTRACT, NEGLIGENCE OR OTHER TORTIOUS ACTION, ARISING OUT OF OR IN
 # CONNECTION WITH THE USE OR PERFORMANCE OF THIS SOFTWARE.
 
+import sys
+
 import pytest
 
 from pyrepl.historical_reader import HistoricalReader
@@ -45,6 +47,10 @@ def test_cmd_instantiation_crash():
     read_spec(spec, HistoricalTestReader)
 
 
+@pytest.mark.skipif(
+    sys.platform == "darwin" and sys.version_info < (3, 10, 9),
+    reason="prepare() hangs due to termios.tcdrain hanging on MacOS https://github.com/python/cpython/issues/97001",
+)
 def test_signal_failure(monkeypatch):
     import os
     import pty
diff --git a/tests/test_readline.py b/tests/test_readline.py
index 10a200a..0992f2f 100644
--- a/tests/test_readline.py
+++ b/tests/test_readline.py
@@ -1,4 +1,5 @@
 import os
+import sys
 import pty
 
 import pytest
@@ -12,6 +13,10 @@ def readline_wrapper():
     return _ReadlineWrapper(slave, slave)
 
 
+@pytest.mark.skipif(
+    sys.platform == "darwin" and sys.version_info < (3, 10, 9),
+    reason="readline() hangs due to termios.tcdrain hanging on MacOS https://github.com/python/cpython/issues/97001",
+)
 def test_readline():
     master, slave = pty.openpty()
     readline_wrapper = _ReadlineWrapper(slave, slave)
@@ -22,6 +27,10 @@ def test_readline():
     assert isinstance(result, bytes)
 
 
+@pytest.mark.skipif(
+    sys.platform == "darwin" and sys.version_info < (3, 10, 9),
+    reason="readline() hangs due to termios.tcdrain hanging on MacOS https://github.com/python/cpython/issues/97001",
+)
 def test_input():
     master, slave = pty.openpty()
     readline_wrapper = _ReadlineWrapper(slave, slave)
@@ -32,6 +41,10 @@ def test_input():
     assert isinstance(result, str)
 
 
+@pytest.mark.skipif(
+    sys.platform == "darwin" and sys.version_info < (3, 10, 9),
+    reason="readline() hangs due to termios.tcdrain hanging on MacOS https://github.com/python/cpython/issues/97001",
+)
 @pytest.mark.parametrize(
     "get_bytes,expected",
     [