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First order statistics
These include local intensity-based statistical measures, computed over the neighbourhood around each voxel, in accordance with the IBSI standard.
For the set of grey levels Xgl = {Xgl,1, Xgl,2, . . . , Xgl,Nv} of Nv neighbouring voxels:
Min : The lowest grey level in Xgl.
Max : The highest grey level in Xgl.
10th percentile : The 10th percentile of Xgl. This is more robust to grey level outliers than the minimum grey level.
90th percentile : The 90th percentile of Xgl. This is more robust to grey level outliers than the maximum grey level.
Median : The sample median of Xgl.
Robust Mean Absolute Deviation : Mean absolute deviation may be influenced by outliers. To increase robustness, the set of grey levels can be restricted to those which lie closer to the center of the distribution.
where P25 and P75 are the 25th and 75th percentiles of Xgl, respectively