diff --git a/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/BeanInfo.java b/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/BeanInfo.java
index 43a6b4647ff264..7de54b7a4acf31 100644
--- a/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/BeanInfo.java
+++ b/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/BeanInfo.java
@@ -535,7 +535,8 @@ private Map<MethodInfo, DecorationInfo> initDecoratedMethods() {
 
         Map<MethodKey, DecorationInfo> candidates = new HashMap<>();
         addDecoratedMethods(candidates, target.get().asClass(), bound,
-                new SubclassSkipPredicate(beanDeployment.getAssignabilityCheck()::isAssignableFrom));
+                new SubclassSkipPredicate(beanDeployment.getAssignabilityCheck()::isAssignableFrom,
+                        beanDeployment.getBeanArchiveIndex()));
 
         Map<MethodInfo, DecorationInfo> decoratedMethods = new HashMap<>(candidates.size());
         for (Entry<MethodKey, DecorationInfo> entry : candidates.entrySet()) {
diff --git a/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/Methods.java b/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/Methods.java
index fea42a8b7725af..1f859fc88c0e51 100644
--- a/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/Methods.java
+++ b/independent-projects/arc/processor/src/main/java/io/quarkus/arc/processor/Methods.java
@@ -161,7 +161,9 @@ static Set<MethodInfo> addInterceptedMethodCandidates(BeanDeployment beanDeploym
             boolean transformUnproxyableClasses) {
         return addInterceptedMethodCandidates(beanDeployment, classInfo, candidates, classLevelBindings,
                 bytecodeTransformerConsumer, transformUnproxyableClasses,
-                new SubclassSkipPredicate(beanDeployment.getAssignabilityCheck()::isAssignableFrom), false);
+                new SubclassSkipPredicate(beanDeployment.getAssignabilityCheck()::isAssignableFrom,
+                        beanDeployment.getBeanArchiveIndex()),
+                false);
     }
 
     static Set<MethodInfo> addInterceptedMethodCandidates(BeanDeployment beanDeployment, ClassInfo classInfo,
@@ -454,12 +456,14 @@ public MethodVisitor visitMethod(int access, String name, String descriptor, Str
     static class SubclassSkipPredicate implements Predicate<MethodInfo> {
 
         private final BiFunction<Type, Type, Boolean> assignableFromFun;
+        private final IndexView beanArchiveIndex;
         private ClassInfo clazz;
         private List<MethodInfo> regularMethods;
         private Set<MethodInfo> bridgeMethods = new HashSet<>();
 
-        public SubclassSkipPredicate(BiFunction<Type, Type, Boolean> assignableFromFun) {
+        public SubclassSkipPredicate(BiFunction<Type, Type, Boolean> assignableFromFun, IndexView beanArchiveIndex) {
             this.assignableFromFun = assignableFromFun;
+            this.beanArchiveIndex = beanArchiveIndex;
         }
 
         void startProcessing(ClassInfo clazz) {
@@ -505,6 +509,20 @@ public boolean test(MethodInfo method) {
                 // Do not skip default methods - public non-abstract instance methods declared in an interface
                 return false;
             }
+
+            List<Type> parameters = method.parameters();
+            if (!parameters.isEmpty() && (beanArchiveIndex != null)) {
+                for (Type type : parameters) {
+                    ClassInfo parameterClassInfo = beanArchiveIndex.getClassByName(type.name());
+                    if (parameterClassInfo == null) {
+                        continue; // hope for the best
+                    }
+                    if (!Modifier.isPublic(parameterClassInfo.flags())) {
+                        return true; // if the parameter is not public, we end up with IllegalAccessError when trying to access the use the load the class
+                    }
+                }
+            }
+
             // Note that we intentionally do not skip final methods here - these are handled later
             return false;
         }
diff --git a/independent-projects/arc/processor/src/test/java/io/quarkus/arc/processor/SubclassSkipPredicateTest.java b/independent-projects/arc/processor/src/test/java/io/quarkus/arc/processor/SubclassSkipPredicateTest.java
index c7b0cb88cd9391..511cd8f78fe06b 100644
--- a/independent-projects/arc/processor/src/test/java/io/quarkus/arc/processor/SubclassSkipPredicateTest.java
+++ b/independent-projects/arc/processor/src/test/java/io/quarkus/arc/processor/SubclassSkipPredicateTest.java
@@ -21,7 +21,7 @@ public class SubclassSkipPredicateTest {
     public void testPredicate() throws IOException {
         IndexView index = Basics.index(Base.class, Submarine.class, Long.class, Number.class);
         AssignabilityCheck assignabilityCheck = new AssignabilityCheck(index, null);
-        SubclassSkipPredicate predicate = new SubclassSkipPredicate(assignabilityCheck::isAssignableFrom);
+        SubclassSkipPredicate predicate = new SubclassSkipPredicate(assignabilityCheck::isAssignableFrom, null);
 
         ClassInfo submarineClass = index.getClassByName(DotName.createSimple(Submarine.class.getName()));
         predicate.startProcessing(submarineClass);