diff --git a/packages/jest-runtime/src/__tests__/Runtime-requireModuleOrMock-test.js b/packages/jest-runtime/src/__tests__/Runtime-requireModuleOrMock-test.js
index 6ab65c7110ed..0bc25d077e6a 100644
--- a/packages/jest-runtime/src/__tests__/Runtime-requireModuleOrMock-test.js
+++ b/packages/jest-runtime/src/__tests__/Runtime-requireModuleOrMock-test.js
@@ -160,3 +160,18 @@ it('automocking is disabled by default', () =>
     );
     expect(exports.setModuleStateValue._isMockFunction).toBe(undefined);
   }));
+
+it('unmocks modules in config.unmockedModulePathPatterns for tests with automock enabled when automock is false', () =>
+  createRuntime(__filename, {
+    automock: false,
+    moduleNameMapper,
+    unmockedModulePathPatterns: ['npm3-main-dep'],
+  }).then(runtime => {
+    const root = runtime.requireModule(runtime.__mockRootPath);
+    root.jest.enableAutomock();
+    const nodeModule = runtime.requireModuleOrMock(runtime.__mockRootPath, 'npm3-main-dep');
+    const moduleData = nodeModule();
+    expect(moduleData.isUnmocked()).toBe(true);
+  })
+);
+
diff --git a/packages/jest-runtime/src/index.js b/packages/jest-runtime/src/index.js
index 1c0becd5a8ee..c669fb25b347 100644
--- a/packages/jest-runtime/src/index.js
+++ b/packages/jest-runtime/src/index.js
@@ -146,7 +146,6 @@ class Runtime {
     this._unmockList = unmockRegExpCache.get(config);
     if (
       !this._unmockList &&
-      config.automock &&
       config.unmockedModulePathPatterns
     ) {
       this._unmockList = new RegExp(