Uberon FAIR Mappings Use Case submission

[gouttegd]

The title of your use case

Mapping anatomical entities across anatomy ontologies

Domain

Biology

Purpose of the mapping

No response

Other purpose of the mapping

Creating a unified multi-species anatomy ontology, allowing consistent annotation of biological data

Type of mapped resources

Entities from from the species-neutral anatomy ontology Uberon and cell type ontology CL, mapped to entities from species-specific anatomy and cell type ontologies such as:

• FlyBase’s Drosophila Anatomy Ontology (FBbt),
• XenBase’s Xenopus Anatomy Ontology (XAO),
• ZFIN’s Zebrafish Anatomy and Development Ontology (ZFA),
• WormBase’s C. elegans Gross Anatomy Ontology (WBbt),
• etc.

Links to an existing mappings

• Mappings between FBbt and Uberon/CL (in SSSOM/TSV format): http://purl.obolibrary.org/obo/fbbt/fbbt.sssom.tsv

Tools used for creating the mapping

Mappings are created by manual curation.

Type of mapping relations

Most mappings between Uberon/CL and the species-specific anatomy ontologies use a handful of dedicated mapping predicates specifically created to represent cross-species mappings:

• https://w3id.org/semapv/vocab/crossSpeciesExactMatch
• https://w3id.org/semapv/vocab/crossSpeciesBroadMatch
• https://w3id.org/semapv/vocab/crossSpeciesNarrowMatch
• https://w3id.org/semapv/vocab/crossSpeciesRelatedMatch

Examples (samples) of different types of mapping implementations

For an example of what we do with the mappings: the Uberon-to-FBbt ontology bridge, used to merge Uberon and FBbt together (a detailed explanation of how this bridge is derived from the Uberon/FBbt mappings is available here.

[matentzn]

Added here: https://mapping-commons.github.io/rda-fair-mappings/case-study/case-study-uberon/