diff --git a/CHANGELOG.md b/CHANGELOG.md
index d5aaca89ee..9904b50a73 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -13,6 +13,8 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 
 - `opentelemetry-sdk-extension-aws` & `opentelemetry-propagator-aws` Release AWS Python SDK Extension as 2.0.1 and AWS Propagator as 1.0.1
   ([#753](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/753))
+- `opentelemetry-instrumentation-pika` Add `_decorate_basic_consume` to ensure post instrumentation `basic_consume` calls are also instrumented.
+  ([#759](https://github.com/open-telemetry/opentelemetry-python-contrib/pull/759))
 
 ### Fixed
 
diff --git a/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/pika_instrumentor.py b/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/pika_instrumentor.py
index a48e46034e..05496f53dd 100644
--- a/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/pika_instrumentor.py
+++ b/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/pika_instrumentor.py
@@ -70,6 +70,7 @@ def _uninstrument_channel_functions(channel: Channel) -> None:
             function = getattr(channel, function_name)
             if hasattr(function, "_original_function"):
                 channel.__setattr__(function_name, function._original_function)
+        unwrap(channel, "basic_consume")
 
     @staticmethod
     def instrument_channel(
@@ -90,6 +91,7 @@ def instrument_channel(
             PikaInstrumentor._instrument_consumers(
                 channel._impl._consumers, tracer
             )
+        PikaInstrumentor._decorate_basic_consume(channel, tracer)
         PikaInstrumentor._instrument_channel_functions(channel, tracer)
 
     @staticmethod
@@ -120,6 +122,33 @@ def wrapper(wrapped, instance, args, kwargs):
 
         wrapt.wrap_function_wrapper(BlockingConnection, "channel", wrapper)
 
+    @staticmethod
+    def _decorate_basic_consume(channel, tracer: Optional[Tracer]) -> None:
+        def wrapper(wrapped, instance, args, kwargs):
+            if not hasattr(channel, "_impl"):
+                _LOG.error(
+                    "Could not find implementation for provided channel!"
+                )
+                return wrapped(*args, **kwargs)
+            current_keys = set(channel._impl._consumers.keys())
+            return_value = wrapped(*args, **kwargs)
+            new_key_list = list(
+                set(channel._impl._consumers.keys()) - current_keys
+            )
+            if not new_key_list:
+                _LOG.error("Could not find added callback")
+                return return_value
+            new_key = new_key_list[0]
+            callback = channel._impl._consumers[new_key]
+            decorated_callback = utils._decorate_callback(
+                callback, tracer, new_key
+            )
+            setattr(decorated_callback, "_original_callback", callback)
+            channel._impl._consumers[new_key] = decorated_callback
+            return return_value
+
+        wrapt.wrap_function_wrapper(channel, "basic_consume", wrapper)
+
     def _instrument(self, **kwargs: Dict[str, Any]) -> None:
         tracer_provider: TracerProvider = kwargs.get("tracer_provider", None)
         self.__setattr__("__opentelemetry_tracer_provider", tracer_provider)
diff --git a/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/utils.py b/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/utils.py
index d1d85b299b..12161d2334 100644
--- a/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/utils.py
+++ b/instrumentation/opentelemetry-instrumentation-pika/src/opentelemetry/instrumentation/pika/utils.py
@@ -41,6 +41,8 @@ def decorated_callback(
     ) -> Any:
         if not properties:
             properties = BasicProperties(headers={})
+        if properties.headers is None:
+            properties.headers = {}
         ctx = propagate.extract(properties.headers, getter=_pika_getter)
         if not ctx:
             ctx = context.get_current()
@@ -74,6 +76,8 @@ def decorated_function(
     ) -> Any:
         if not properties:
             properties = BasicProperties(headers={})
+        if properties.headers is None:
+            properties.headers = {}
         ctx = context.get_current()
         span = _get_span(
             tracer,
diff --git a/instrumentation/opentelemetry-instrumentation-pika/tests/test_pika_instrumentation.py b/instrumentation/opentelemetry-instrumentation-pika/tests/test_pika_instrumentation.py
index 508d49c3bd..da2a940b5b 100644
--- a/instrumentation/opentelemetry-instrumentation-pika/tests/test_pika_instrumentation.py
+++ b/instrumentation/opentelemetry-instrumentation-pika/tests/test_pika_instrumentation.py
@@ -45,12 +45,16 @@ def test_instrument_api(self) -> None:
     @mock.patch(
         "opentelemetry.instrumentation.pika.PikaInstrumentor._instrument_channel_functions"
     )
+    @mock.patch(
+        "opentelemetry.instrumentation.pika.PikaInstrumentor._decorate_basic_consume"
+    )
     @mock.patch(
         "opentelemetry.instrumentation.pika.PikaInstrumentor._instrument_consumers"
     )
     def test_instrument(
         self,
         instrument_consumers: mock.MagicMock,
+        instrument_basic_consume: mock.MagicMock,
         instrument_channel_functions: mock.MagicMock,
     ):
         PikaInstrumentor.instrument_channel(channel=self.channel)
@@ -58,6 +62,7 @@ def test_instrument(
             self.channel, "_is_instrumented_by_opentelemetry"
         ), "channel is not marked as instrumented!"
         instrument_consumers.assert_called_once()
+        instrument_basic_consume.assert_called_once()
         instrument_channel_functions.assert_called_once()
 
     @mock.patch("opentelemetry.instrumentation.pika.utils._decorate_callback")
diff --git a/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py b/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py
index 5f63b4af5e..45741f0821 100644
--- a/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py
+++ b/opentelemetry-instrumentation/src/opentelemetry/instrumentation/utils.py
@@ -17,6 +17,7 @@
 from wrapt import ObjectProxy
 
 # pylint: disable=unused-import
+# pylint: disable=E0611
 from opentelemetry.context import _SUPPRESS_INSTRUMENTATION_KEY  # noqa: F401
 from opentelemetry.trace import StatusCode