diff --git a/extensions/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java b/extensions/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java
index c8a4aae8b8132c..1e67bf64acf958 100755
--- a/extensions/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java
+++ b/extensions/resteasy-server-common/deployment/src/main/java/io/quarkus/resteasy/server/common/deployment/ResteasyServerCommonProcessor.java
@@ -259,6 +259,10 @@ public void build(
                 String className = implementor.name().toString();
                 reflectiveClass.produce(new ReflectiveClassBuildItem(true, true, className));
                 scannedResources.putIfAbsent(implementor.name(), implementor);
+
+                if (!implementor.hasNoArgsConstructor()) {
+                    withoutDefaultCtor.put(implementor.name(), implementor);
+                }
             }
         }
 
diff --git a/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/InterfaceResource.java b/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/InterfaceResource.java
new file mode 100644
index 00000000000000..09325e0a18e037
--- /dev/null
+++ b/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/InterfaceResource.java
@@ -0,0 +1,15 @@
+package io.quarkus.resteasy.test;
+
+import javax.ws.rs.GET;
+import javax.ws.rs.Path;
+import javax.ws.rs.Produces;
+import javax.ws.rs.core.MediaType;
+
+@Path("/inter")
+public interface InterfaceResource {
+
+    @Path("/hello")
+    @GET
+    @Produces(MediaType.TEXT_PLAIN)
+    String hello();
+}
diff --git a/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/InterfaceResourceImpl.java b/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/InterfaceResourceImpl.java
new file mode 100644
index 00000000000000..f52daaaeaf7465
--- /dev/null
+++ b/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/InterfaceResourceImpl.java
@@ -0,0 +1,15 @@
+package io.quarkus.resteasy.test;
+
+public class InterfaceResourceImpl implements InterfaceResource {
+
+    private Service service;
+
+    public InterfaceResourceImpl(Service service) {
+        this.service = service;
+    }
+
+    @Override
+    public String hello() {
+        return "hello from impl";
+    }
+}
diff --git a/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/RestEasyDevModeTestCase.java b/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/RestEasyDevModeTestCase.java
index 61192b4583dd08..5ad185a6670192 100644
--- a/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/RestEasyDevModeTestCase.java
+++ b/extensions/resteasy/deployment/src/test/java/io/quarkus/resteasy/test/RestEasyDevModeTestCase.java
@@ -20,6 +20,9 @@ public class RestEasyDevModeTestCase {
             .setArchiveProducer(() -> ShrinkWrap.create(JavaArchive.class)
                     .addClass(PostResource.class)
                     .addClass(GreetingResource.class)
+                    .addClass(InterfaceResource.class)
+                    .addClass(InterfaceResourceImpl.class)
+                    .addClass(Service.class)
                     .addAsResource("config-test.properties", "application.properties"));
 
     @Test
@@ -54,4 +57,11 @@ public void testConfigHotReplacement() {
                 .statusCode(200)
                 .body(is("hi from dev mode"));
     }
+
+    @Test
+    public void testInterfaceImplementation() {
+        RestAssured.when().get("/inter/hello").then()
+                .statusCode(200)
+                .body(is("hello from impl"));
+    }
 }