diff --git a/ext/exif/exif.c b/ext/exif/exif.c
index 5096f69001b9..c0bf6f789159 100644
--- a/ext/exif/exif.c
+++ b/ext/exif/exif.c
@@ -4395,7 +4395,7 @@ static bool exif_read_from_impl(image_info_type *ImageInfo, php_stream *stream,
 	ImageInfo->FileName			= NULL;
 
 	if (php_stream_is(ImageInfo->infile, PHP_STREAM_IS_STDIO)) {
-		if (VCWD_STAT(stream->orig_path, &st) >= 0) {
+		if (stream->orig_path && VCWD_STAT(stream->orig_path, &st) >= 0) {
 			zend_string *base;
 			if ((st.st_mode & S_IFMT) != S_IFREG) {
 				exif_error_docref(NULL EXIFERR_CC, ImageInfo, E_WARNING, "Not a file");
diff --git a/ext/exif/tests/gh16409.phpt b/ext/exif/tests/gh16409.phpt
new file mode 100644
index 000000000000..c2c54d839e01
--- /dev/null
+++ b/ext/exif/tests/gh16409.phpt
@@ -0,0 +1,12 @@
+--TEST--
+GH-16409 (Segfault in exif_thumbnail when not dealing with a real file)
+--EXTENSIONS--
+exif
+--FILE--
+<?php
+$stream = popen('echo 1', 'r');
+var_dump(exif_thumbnail($stream, $pipes, $stream, $pipes));
+?>
+--EXPECTF--
+Warning: exif_thumbnail(): File too small (0) in %s on line %d
+bool(false)%A