diff --git a/setup.py b/setup.py
index 28a6903..5cc02cd 100644
--- a/setup.py
+++ b/setup.py
@@ -13,8 +13,6 @@
     include_package_data=True,
     install_requires=[
         'automat<22.10.0',  # Twisted dep, newer versions don't work with ancient Python.
-        'cryptography<3.2',  # To see if this avoids "undefined symbol: FIPS_mode".
-        'pyOpenSSL<21',  # Maybe?
         'Twisted>=20.3.0,<21.0.0',
         'vumi>=0.6.19',
     ],