diff --git a/integrationExamples/gpt/prebidServer_example.html b/integrationExamples/gpt/prebidServer_example.html
index 7761178efa8..37902edd979 100644
--- a/integrationExamples/gpt/prebidServer_example.html
+++ b/integrationExamples/gpt/prebidServer_example.html
@@ -56,10 +56,10 @@
           s2sConfig : {
             accountId : '1',
             enabled : true, //default value set to false
+            defaultVendor: 'appnexus',
             bidders : ['appnexus'],
             timeout : 1000, //default value is 1000
             adapter : 'prebidServer', //if we have any other s2s adapter, default value is s2s
-            endpoint : 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
           }
         });
 
diff --git a/modules/appnexusBidAdapter.js b/modules/appnexusBidAdapter.js
index 6feec56e919..deb091fb2b7 100644
--- a/modules/appnexusBidAdapter.js
+++ b/modules/appnexusBidAdapter.js
@@ -11,6 +11,7 @@ import { getStorageManager } from '../src/storageManager.js';
 
 const BIDDER_CODE = 'appnexus';
 const URL = 'https://ib.adnxs.com/ut/v3/prebid';
+const URL_SIMPLE = 'https://ib.adnxs-simple.com/ut/v3/prebid';
 const VIDEO_TARGETING = ['id', 'minduration', 'maxduration',
   'skippable', 'playback_method', 'frameworks', 'context', 'skipoffset'];
 const USER_PARAMS = ['age', 'externalUid', 'segments', 'gender', 'dnt', 'language'];
@@ -53,9 +54,9 @@ const NATIVE_MAPPING = {
 };
 const SOURCE = 'pbjs';
 const MAX_IMPS_PER_REQUEST = 15;
-const mappingFileUrl = 'https://acdn.adnxs.com/prebid/appnexus-mapping/mappings.json';
+const mappingFileUrl = 'https://acdn.adnxs-simple.com/prebid/appnexus-mapping/mappings.json';
 const SCRIPT_TAG_START = '<script';
-const VIEWABILITY_URL_START = /\/\/cdn\.adnxs\.com\/v/;
+const VIEWABILITY_URL_START = /\/\/cdn\.adnxs\.com\/v|\/\/cdn\.adnxs\-simple\.com\/v/;
 const VIEWABILITY_FILE_NAME = 'trk.js';
 const GVLID = 32;
 const storage = getStorageManager(GVLID, BIDDER_CODE);
@@ -326,8 +327,8 @@ export const spec = {
     }
   },
 
-  getUserSyncs: function (syncOptions) {
-    if (syncOptions.iframeEnabled) {
+  getUserSyncs: function (syncOptions, responses, gdprConsent) {
+    if (syncOptions.iframeEnabled && hasPurpose1Consent({gdprConsent})) {
       return [{
         type: 'iframe',
         url: 'https://acdn.adnxs.com/dmp/async_usersync.html'
@@ -483,10 +484,10 @@ function hasPurpose1Consent(bidderRequest) {
 function formatRequest(payload, bidderRequest) {
   let request = [];
   let options = {};
+  let endpointUrl = URL;
+
   if (!hasPurpose1Consent(bidderRequest)) {
-    options = {
-      withCredentials: false
-    }
+    endpointUrl = URL_SIMPLE;
   }
 
   if (utils.getParameterByName('apn_test').toUpperCase() === 'TRUE' || config.getConfig('apn_test') === true) {
@@ -503,7 +504,7 @@ function formatRequest(payload, bidderRequest) {
       const payloadString = JSON.stringify(clonedPayload);
       request.push({
         method: 'POST',
-        url: URL,
+        url: endpointUrl,
         data: payloadString,
         bidderRequest,
         options
@@ -513,7 +514,7 @@ function formatRequest(payload, bidderRequest) {
     const payloadString = JSON.stringify(payload);
     request = {
       method: 'POST',
-      url: URL,
+      url: endpointUrl,
       data: payloadString,
       bidderRequest,
       options
diff --git a/modules/prebidServerBidAdapter/config.js b/modules/prebidServerBidAdapter/config.js
index 3a8f0b05f43..92a8f5deaa5 100644
--- a/modules/prebidServerBidAdapter/config.js
+++ b/modules/prebidServerBidAdapter/config.js
@@ -3,22 +3,40 @@ export const S2S_VENDORS = {
   'appnexus': {
     adapter: 'prebidServer',
     enabled: true,
-    endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction',
-    syncEndpoint: 'https://prebid.adnxs.com/pbs/v1/cookie_sync',
+    endpoint: {
+      p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction',
+      noP1Consent: 'https://prebid.adnxs-simple.com/pbs/v1/openrtb2/auction'
+    },
+    syncEndpoint: {
+      p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync',
+      noP1Consent: 'https://prebid.adnxs-simple.com/pbs/v1/cookie_sync'
+    },
     timeout: 1000
   },
   'rubicon': {
     adapter: 'prebidServer',
     enabled: true,
-    endpoint: 'https://prebid-server.rubiconproject.com/openrtb2/auction',
-    syncEndpoint: 'https://prebid-server.rubiconproject.com/cookie_sync',
+    endpoint: {
+      p1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction',
+      noP1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction',
+    },
+    syncEndpoint: {
+      p1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync',
+      noP1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync',
+    },
     timeout: 500
   },
   'openx': {
     adapter: 'prebidServer',
     enabled: true,
-    endpoint: 'https://prebid.openx.net/openrtb2/auction',
-    syncEndpoint: 'https://prebid.openx.net/cookie_sync',
+    endpoint: {
+      p1Consent: 'https://prebid.openx.net/openrtb2/auction',
+      noP1Consent: 'https://prebid.openx.net/openrtb2/auction'
+    },
+    syncEndpoint: {
+      p1Consent: 'https://prebid.openx.net/cookie_sync',
+      noP1Consent: 'https://prebid.openx.net/cookie_sync'
+    },
     timeout: 1000
   }
 }
diff --git a/modules/prebidServerBidAdapter/index.js b/modules/prebidServerBidAdapter/index.js
index ff326f25840..a1fd1cc34e0 100644
--- a/modules/prebidServerBidAdapter/index.js
+++ b/modules/prebidServerBidAdapter/index.js
@@ -124,6 +124,17 @@ function validateConfigRequiredProps(option) {
   }
 }
 
+// temporary change to modify the s2sConfig for new format used for endpoint URLs;
+// could be removed later as part of a major release, if we decide to not support the old format
+function formatUrlParams(option) {
+  ['endpoint', 'syncEndpoint'].forEach((prop) => {
+    if (utils.isStr(option[prop])) {
+      let temp = option[prop];
+      option[prop] = { p1Consent: temp, noP1Consent: temp };
+    }
+  });
+}
+
 /**
  * @param {(S2SConfig[]|S2SConfig)} options
  */
@@ -135,6 +146,7 @@ function setS2sConfig(options) {
 
   const activeBidders = [];
   const optionsValid = normalizedOptions.every((option, i, array) => {
+    formatUrlParams(options);
     const updateSuccess = updateConfigDefaultVendor(option);
     if (updateSuccess !== false) {
       const valid = validateConfigRequiredProps(option);
@@ -205,7 +217,7 @@ function queueSync(bidderCodes, gdprConsent, uspConsent, s2sConfig) {
   }
 
   const jsonPayload = JSON.stringify(payload);
-  ajax(s2sConfig.syncEndpoint,
+  ajax(getMatchingConsentUrl(s2sConfig.syncEndpoint, gdprConsent),
     (response) => {
       try {
         response = JSON.parse(response);
@@ -285,11 +297,20 @@ function doBidderSync(type, url, bidder, done) {
  *
  * @param {Array} bidders a list of bidder names
  */
-function doClientSideSyncs(bidders) {
+function doClientSideSyncs(bidders, gdprConsent, uspConsent) {
   bidders.forEach(bidder => {
     let clientAdapter = adapterManager.getBidAdapter(bidder);
     if (clientAdapter && clientAdapter.registerSyncs) {
-      clientAdapter.registerSyncs([]);
+      config.runWithBidder(
+        bidder,
+        utils.bind.call(
+          clientAdapter.registerSyncs,
+          clientAdapter,
+          [],
+          gdprConsent,
+          uspConsent
+        )
+      );
     }
   });
 }
@@ -978,6 +999,29 @@ function bidWonHandler(bid) {
   }
 }
 
+function hasPurpose1Consent(gdprConsent) {
+  let result = true;
+  if (gdprConsent) {
+    if (gdprConsent.gdprApplies && gdprConsent.apiVersion === 2) {
+      result = !!(utils.deepAccess(gdprConsent, 'vendorData.purpose.consents.1') === true);
+    }
+  }
+  return result;
+}
+
+function getMatchingConsentUrl(urlProp, gdprConsent) {
+  return hasPurpose1Consent(gdprConsent) ? urlProp.p1Consent : urlProp.noP1Consent;
+}
+
+function getConsentData(bidRequests) {
+  let gdprConsent, uspConsent;
+  if (Array.isArray(bidRequests) && bidRequests.length > 0) {
+    gdprConsent = bidRequests[0].gdprConsent;
+    uspConsent = bidRequests[0].uspConsent;
+  }
+  return { gdprConsent, uspConsent };
+}
+
 /**
  * Bidder adapter for Prebid Server
  */
@@ -987,6 +1031,7 @@ export function PrebidServer() {
   /* Prebid executes this function when the page asks to send out bid requests */
   baseAdapter.callBids = function(s2sBidRequest, bidRequests, addBidResponse, done, ajax) {
     const adUnits = utils.deepClone(s2sBidRequest.ad_units);
+    let { gdprConsent, uspConsent } = getConsentData(bidRequests);
 
     // at this point ad units should have a size array either directly or mapped so filter for that
     const validAdUnits = adUnits.filter(unit =>
@@ -1000,13 +1045,7 @@ export function PrebidServer() {
       .filter(utils.uniques);
 
     if (Array.isArray(_s2sConfigs)) {
-      if (s2sBidRequest.s2sConfig && s2sBidRequest.s2sConfig.syncEndpoint) {
-        let gdprConsent, uspConsent;
-        if (Array.isArray(bidRequests) && bidRequests.length > 0) {
-          gdprConsent = bidRequests[0].gdprConsent;
-          uspConsent = bidRequests[0].uspConsent;
-        }
-
+      if (s2sBidRequest.s2sConfig && s2sBidRequest.s2sConfig.syncEndpoint && getMatchingConsentUrl(s2sBidRequest.s2sConfig.syncEndpoint, gdprConsent)) {
         let syncBidders = s2sBidRequest.s2sConfig.bidders
           .map(bidder => adapterManager.aliasRegistry[bidder] || bidder)
           .filter((bidder, index, array) => (array.indexOf(bidder) === index));
@@ -1019,7 +1058,7 @@ export function PrebidServer() {
       utils.logInfo('BidRequest: ' + requestJson);
       if (request && requestJson) {
         ajax(
-          s2sBidRequest.s2sConfig.endpoint,
+          getMatchingConsentUrl(s2sBidRequest.s2sConfig.endpoint, gdprConsent),
           {
             success: response => handleResponse(response, requestedBidders, bidRequests, addBidResponse, done, s2sBidRequest.s2sConfig),
             error: done
@@ -1035,6 +1074,7 @@ export function PrebidServer() {
   function handleResponse(response, requestedBidders, bidderRequests, addBidResponse, done, s2sConfig) {
     let result;
     let bids = [];
+    let { gdprConsent, uspConsent } = getConsentData(bidderRequests);
 
     try {
       result = JSON.parse(response);
@@ -1061,7 +1101,7 @@ export function PrebidServer() {
     }
 
     done();
-    doClientSideSyncs(requestedBidders);
+    doClientSideSyncs(requestedBidders, gdprConsent, uspConsent);
   }
 
   // Listen for bid won to call wurl
diff --git a/test/spec/modules/appnexusBidAdapter_spec.js b/test/spec/modules/appnexusBidAdapter_spec.js
index 3a3f4effcb8..935bc23be03 100644
--- a/test/spec/modules/appnexusBidAdapter_spec.js
+++ b/test/spec/modules/appnexusBidAdapter_spec.js
@@ -796,7 +796,7 @@ describe('AppNexusAdapter', function () {
       config.getConfig.restore();
     });
 
-    it('should set withCredentials to false if purpose 1 consent is not given', function () {
+    it('should set simple domain variant if purpose 1 consent is not given', function () {
       let consentString = 'BOJ8RZsOJ8RZsABAB8AAAAAZ+A==';
       let bidderRequest = {
         'bidderCode': 'appnexus',
@@ -819,7 +819,7 @@ describe('AppNexusAdapter', function () {
       bidderRequest.bids = bidRequests;
 
       const request = spec.buildRequests(bidRequests, bidderRequest);
-      expect(request.options).to.deep.equal({withCredentials: false});
+      expect(request.url).to.equal('https://ib.adnxs-simple.com/ut/v3/prebid');
     });
 
     it('should populate eids when supported userIds are available', function () {
diff --git a/test/spec/modules/prebidServerBidAdapter_spec.js b/test/spec/modules/prebidServerBidAdapter_spec.js
index 937d67677d9..b7be4948b0e 100644
--- a/test/spec/modules/prebidServerBidAdapter_spec.js
+++ b/test/spec/modules/prebidServerBidAdapter_spec.js
@@ -15,7 +15,10 @@ let CONFIG = {
   bidders: ['appnexus'],
   timeout: 1000,
   cacheMarkup: 2,
-  endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+  endpoint: {
+    p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction',
+    noP1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+  }
 };
 
 const REQUEST = {
@@ -513,7 +516,7 @@ describe('S2S Adapter', function () {
 
     it('should default video placement if not defined and instream', function () {
       let ortb2Config = utils.deepClone(CONFIG);
-      ortb2Config.endpoint = 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction';
+      ortb2Config.endpoint.p1Consent = 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction';
 
       config.setConfig({ s2sConfig: ortb2Config });
 
@@ -592,7 +595,7 @@ describe('S2S Adapter', function () {
 
       it('check gdpr info gets added into cookie_sync request: have consent data', function () {
         let cookieSyncConfig = utils.deepClone(CONFIG);
-        cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+        cookieSyncConfig.syncEndpoint = { p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync' };
 
         let consentConfig = { consentManagement: { cmpApi: 'iab' }, s2sConfig: cookieSyncConfig };
         config.setConfig(consentConfig);
@@ -618,7 +621,7 @@ describe('S2S Adapter', function () {
 
       it('check gdpr info gets added into cookie_sync request: have consent data but gdprApplies is false', function () {
         let cookieSyncConfig = utils.deepClone(CONFIG);
-        cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+        cookieSyncConfig.syncEndpoint = { p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync' };
 
         let consentConfig = { consentManagement: { cmpApi: 'iab' }, s2sConfig: cookieSyncConfig };
         config.setConfig(consentConfig);
@@ -641,7 +644,7 @@ describe('S2S Adapter', function () {
 
       it('checks gdpr info gets added to cookie_sync request: applies is false', function () {
         let cookieSyncConfig = utils.deepClone(CONFIG);
-        cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+        cookieSyncConfig.syncEndpoint = { p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync' };
 
         let consentConfig = { consentManagement: { cmpApi: 'iab' }, s2sConfig: cookieSyncConfig };
         config.setConfig(consentConfig);
@@ -690,7 +693,7 @@ describe('S2S Adapter', function () {
 
       it('is added to cookie_sync request when in bidRequest', function () {
         let cookieSyncConfig = utils.deepClone(CONFIG);
-        cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+        cookieSyncConfig.syncEndpoint = { p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync' };
         config.setConfig({ s2sConfig: cookieSyncConfig });
 
         let uspBidRequest = utils.deepClone(BID_REQUESTS);
@@ -742,7 +745,7 @@ describe('S2S Adapter', function () {
 
       it('is added to cookie_sync request when in bidRequest', function () {
         let cookieSyncConfig = utils.deepClone(CONFIG);
-        cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+        cookieSyncConfig.syncEndpoint = { p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync' };
         config.setConfig({ s2sConfig: cookieSyncConfig });
 
         let consentBidRequest = utils.deepClone(BID_REQUESTS);
@@ -789,7 +792,9 @@ describe('S2S Adapter', function () {
 
     it('adds device and app objects to request for OpenRTB', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        endpoint: {
+          p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        }
       });
 
       const _config = {
@@ -1094,7 +1099,9 @@ describe('S2S Adapter', function () {
 
     it('skips pbs alias when skipPbsAliasing is enabled in adapter', function() {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        endpoint: {
+          p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        }
       });
       config.setConfig({ s2sConfig: s2sConfig });
 
@@ -1123,7 +1130,9 @@ describe('S2S Adapter', function () {
 
     it('skips dynamic aliases to request when skipPbsAliasing enabled', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        endpoint: {
+          p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        }
       });
       config.setConfig({ s2sConfig: s2sConfig });
 
@@ -1155,7 +1164,9 @@ describe('S2S Adapter', function () {
 
     it('converts appnexus params to expected format for PBS', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        endpoint: {
+          p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        }
       });
       config.setConfig({ s2sConfig: s2sConfig });
 
@@ -1184,7 +1195,7 @@ describe('S2S Adapter', function () {
 
     it('adds limit to the cookie_sync request if userSyncLimit is greater than 0', function () {
       let cookieSyncConfig = utils.deepClone(CONFIG);
-      cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+      cookieSyncConfig.syncEndpoint = { p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync' };
       cookieSyncConfig.userSyncLimit = 1;
 
       const s2sBidRequest = utils.deepClone(REQUEST);
@@ -1203,7 +1214,7 @@ describe('S2S Adapter', function () {
 
     it('does not add limit to cooke_sync request if userSyncLimit is missing or 0', function () {
       let cookieSyncConfig = utils.deepClone(CONFIG);
-      cookieSyncConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+      cookieSyncConfig.syncEndpoint = { p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync' };
       config.setConfig({ s2sConfig: cookieSyncConfig });
 
       const s2sBidRequest = utils.deepClone(REQUEST);
@@ -2020,7 +2031,9 @@ describe('S2S Adapter', function () {
 
     it('handles OpenRTB video responses', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
 
@@ -2042,7 +2055,9 @@ describe('S2S Adapter', function () {
 
     it('handles response cache from ext.prebid.cache.vastXml', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
       const cacheResponse = utils.deepClone(RESPONSE_OPENRTB_VIDEO);
@@ -2071,7 +2086,9 @@ describe('S2S Adapter', function () {
 
     it('add adserverTargeting object to bids when ext.prebid.targeting is defined', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
       const cacheResponse = utils.deepClone(RESPONSE_OPENRTB_VIDEO);
@@ -2102,7 +2119,9 @@ describe('S2S Adapter', function () {
 
     it('handles response cache from ext.prebid.targeting', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
       const cacheResponse = utils.deepClone(RESPONSE_OPENRTB_VIDEO);
@@ -2130,7 +2149,9 @@ describe('S2S Adapter', function () {
 
     it('handles response cache from ext.prebid.targeting with wurl', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
       const cacheResponse = utils.deepClone(RESPONSE_OPENRTB_VIDEO);
@@ -2157,7 +2178,9 @@ describe('S2S Adapter', function () {
 
     it('handles response cache from ext.prebid.targeting with wurl and removes invalid targeting', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
       const cacheResponse = utils.deepClone(RESPONSE_OPENRTB_VIDEO);
@@ -2192,7 +2215,9 @@ describe('S2S Adapter', function () {
 
     it('add request property pbsBidId with ext.prebid.bidid value', function () {
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
       const cacheResponse = utils.deepClone(RESPONSE_OPENRTB_VIDEO);
@@ -2216,7 +2241,9 @@ describe('S2S Adapter', function () {
         bidId: '123'
       });
       const s2sConfig = Object.assign({}, CONFIG, {
-        endpoint: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        endpoint: {
+          p1Consent: 'https://prebidserverurl/openrtb2/auction?querystring=param'
+        }
       });
       config.setConfig({ s2sConfig });
 
@@ -2260,7 +2287,9 @@ describe('S2S Adapter', function () {
 
       config.setConfig({
         s2sConfig: Object.assign({}, CONFIG, {
-          endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+          endpoint: {
+            p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+          }
         })
       });
     });
@@ -2349,7 +2378,9 @@ describe('S2S Adapter', function () {
         bidders: ['appnexus'],
         timeout: 1000,
         adapter: 'prebidServer',
-        endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        endpoint: {
+          p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        }
       };
 
       config.setConfig({ s2sConfig: options });
@@ -2362,7 +2393,9 @@ describe('S2S Adapter', function () {
         enabled: true,
         timeout: 1000,
         adapter: 's2s',
-        endpoint: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        endpoint: {
+          p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction'
+        }
       };
 
       config.setConfig({ s2sConfig: options });
@@ -2409,8 +2442,8 @@ describe('S2S Adapter', function () {
       expect(vendorConfig).to.have.property('adapter', 'prebidServer');
       expect(vendorConfig.bidders).to.deep.equal(['appnexus']);
       expect(vendorConfig.enabled).to.be.true;
-      expect(vendorConfig).to.have.property('endpoint', 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction');
-      expect(vendorConfig).to.have.property('syncEndpoint', 'https://prebid.adnxs.com/pbs/v1/cookie_sync');
+      expect(vendorConfig.endpoint).to.deep.equal({p1Consent: 'https://prebid.adnxs.com/pbs/v1/openrtb2/auction', noP1Consent: 'https://prebid.adnxs-simple.com/pbs/v1/openrtb2/auction'});
+      expect(vendorConfig.syncEndpoint).to.deep.equal({p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync', noP1Consent: 'https://prebid.adnxs-simple.com/pbs/v1/cookie_sync'});
       expect(vendorConfig).to.have.property('timeout', 750);
     });
 
@@ -2430,8 +2463,8 @@ describe('S2S Adapter', function () {
       expect(vendorConfig).to.have.property('adapter', 'prebidServer');
       expect(vendorConfig.bidders).to.deep.equal(['rubicon']);
       expect(vendorConfig.enabled).to.be.true;
-      expect(vendorConfig).to.have.property('endpoint', 'https://prebid-server.rubiconproject.com/openrtb2/auction');
-      expect(vendorConfig).to.have.property('syncEndpoint', 'https://prebid-server.rubiconproject.com/cookie_sync');
+      expect(vendorConfig.endpoint).to.deep.equal({p1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction', noP1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction'});
+      expect(vendorConfig.syncEndpoint).to.deep.equal({p1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync', noP1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync'});
       expect(vendorConfig).to.have.property('timeout', 750);
     });
 
@@ -2450,8 +2483,8 @@ describe('S2S Adapter', function () {
         'bidders': ['rubicon'],
         'defaultVendor': 'rubicon',
         'enabled': true,
-        'endpoint': 'https://prebid-server.rubiconproject.com/openrtb2/auction',
-        'syncEndpoint': 'https://prebid-server.rubiconproject.com/cookie_sync',
+        'endpoint': {p1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction', noP1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction'},
+        'syncEndpoint': {p1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync', noP1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync'},
         'timeout': 750
       })
     });
@@ -2472,8 +2505,8 @@ describe('S2S Adapter', function () {
         accountId: 'abc',
         bidders: ['rubicon'],
         defaultVendor: 'rubicon',
-        endpoint: 'https://prebid-server.rubiconproject.com/openrtb2/auction',
-        syncEndpoint: 'https://prebid-server.rubiconproject.com/cookie_sync',
+        endpoint: {p1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction', noP1Consent: 'https://prebid-server.rubiconproject.com/openrtb2/auction'},
+        syncEndpoint: {p1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync', noP1Consent: 'https://prebid-server.rubiconproject.com/cookie_sync'},
       })
     });
 
@@ -2521,7 +2554,7 @@ describe('S2S Adapter', function () {
 
       // Add syncEndpoint so that the request goes to the User Sync endpoint
       // Modify the bidders property to include an alias for Rubicon adapter
-      s2sConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+      s2sConfig.syncEndpoint = {p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync'};
       s2sConfig.bidders = ['appnexus', 'rubicon-alias'];
 
       const s2sBidRequest = utils.deepClone(REQUEST);
@@ -2592,7 +2625,7 @@ describe('S2S Adapter', function () {
     it('should add cooperative sync flag to cookie_sync request if property is present', function () {
       let s2sConfig = utils.deepClone(CONFIG);
       s2sConfig.coopSync = false;
-      s2sConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+      s2sConfig.syncEndpoint = {p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync'};
 
       const s2sBidRequest = utils.deepClone(REQUEST);
       s2sBidRequest.s2sConfig = s2sConfig;
@@ -2607,7 +2640,7 @@ describe('S2S Adapter', function () {
 
     it('should not add cooperative sync flag to cookie_sync request if property is not present', function () {
       let s2sConfig = utils.deepClone(CONFIG);
-      s2sConfig.syncEndpoint = 'https://prebid.adnxs.com/pbs/v1/cookie_sync';
+      s2sConfig.syncEndpoint = {p1Consent: 'https://prebid.adnxs.com/pbs/v1/cookie_sync'};
 
       const s2sBidRequest = utils.deepClone(REQUEST);
       s2sBidRequest.s2sConfig = s2sConfig;