diff --git a/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SimpleQuarkusRestTestCase.java b/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SimpleQuarkusRestTestCase.java
index 51ef18e647cc1..9dea4e08961c7 100644
--- a/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SimpleQuarkusRestTestCase.java
+++ b/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SimpleQuarkusRestTestCase.java
@@ -8,6 +8,7 @@
 
 import java.util.function.Supplier;
 
+import org.apache.http.HttpStatus;
 import org.hamcrest.Matchers;
 import org.jboss.shrinkwrap.api.ShrinkWrap;
 import org.jboss.shrinkwrap.api.spec.JavaArchive;
@@ -19,6 +20,7 @@
 
 import io.quarkus.test.QuarkusUnitTest;
 import io.restassured.RestAssured;
+import io.restassured.http.ContentType;
 import io.restassured.http.Headers;
 
 public class SimpleQuarkusRestTestCase {
@@ -107,6 +109,12 @@ public void testSubResource() {
                 .then().body(Matchers.equalTo("otherSub"));
         RestAssured.get("/simple/sub")
                 .then().body(Matchers.equalTo("sub"));
+
+        RestAssured.with()
+                .contentType(ContentType.JSON)
+                .body("{\"test\": true}")
+                .patch("/simple/sub/patch/text")
+                .then().statusCode(HttpStatus.SC_UNSUPPORTED_MEDIA_TYPE);
     }
 
     @Test
diff --git a/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SubResource.java b/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SubResource.java
index 00b37fdf42c6c..e1546a77d6fc8 100644
--- a/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SubResource.java
+++ b/extensions/resteasy-reactive/quarkus-resteasy-reactive/deployment/src/test/java/io/quarkus/resteasy/reactive/server/test/simple/SubResource.java
@@ -1,7 +1,10 @@
 package io.quarkus.resteasy.reactive.server.test.simple;
 
+import javax.ws.rs.Consumes;
 import javax.ws.rs.GET;
+import javax.ws.rs.PATCH;
 import javax.ws.rs.Path;
+import javax.ws.rs.core.MediaType;
 
 public class SubResource {
 
@@ -15,4 +18,11 @@ public String sub() {
     public String otherPath() {
         return "otherSub";
     }
+
+    @Path("patch/text")
+    @PATCH
+    @Consumes(MediaType.TEXT_PLAIN)
+    public String patchWithTextPlain(String patch) {
+        return "test-value: " + patch;
+    }
 }
diff --git a/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/core/startup/RuntimeResourceDeployment.java b/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/core/startup/RuntimeResourceDeployment.java
index 67118258789de..1ca909d8bd1b9 100644
--- a/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/core/startup/RuntimeResourceDeployment.java
+++ b/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/core/startup/RuntimeResourceDeployment.java
@@ -312,8 +312,8 @@ public RuntimeResource buildResourceMethod(ResourceClass clazz,
                 // we only need to parse the signature and create generic type when the declared type differs from the type
                 genericType = TypeSignatureParser.parse(bodyParameter.signature);
             }
-            handlers.add(new RequestDeserializeHandler(typeClass, genericType,
-                    consumesMediaTypes.isEmpty() ? null : consumesMediaTypes.get(0), serialisers, bodyParameterIndex));
+            handlers.add(new RequestDeserializeHandler(typeClass, genericType, consumesMediaTypes, serialisers,
+                    bodyParameterIndex));
         }
 
         // given that we may inject form params in the endpoint we need to make sure we read the body before
diff --git a/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/handlers/RequestDeserializeHandler.java b/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/handlers/RequestDeserializeHandler.java
index 0203a0285b238..701946a95ca5c 100644
--- a/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/handlers/RequestDeserializeHandler.java
+++ b/independent-projects/resteasy-reactive/server/runtime/src/main/java/org/jboss/resteasy/reactive/server/handlers/RequestDeserializeHandler.java
@@ -3,6 +3,7 @@
 import java.io.IOException;
 import java.lang.annotation.Annotation;
 import java.lang.reflect.Type;
+import java.util.Collections;
 import java.util.List;
 
 import javax.ws.rs.BadRequestException;
@@ -17,6 +18,7 @@
 import javax.ws.rs.ext.ReaderInterceptor;
 
 import org.jboss.logging.Logger;
+import org.jboss.resteasy.reactive.common.util.MediaTypeHelper;
 import org.jboss.resteasy.reactive.server.core.ResteasyReactiveRequestContext;
 import org.jboss.resteasy.reactive.server.core.ServerSerialisers;
 import org.jboss.resteasy.reactive.server.jaxrs.ReaderInterceptorContextImpl;
@@ -29,30 +31,40 @@ public class RequestDeserializeHandler implements ServerRestHandler {
 
     private final Class<?> type;
     private final Type genericType;
-    private final MediaType mediaType;
+    private final List<MediaType> acceptableMediaTypes;
     private final ServerSerialisers serialisers;
     private final int parameterIndex;
 
-    public RequestDeserializeHandler(Class<?> type, Type genericType, MediaType mediaType, ServerSerialisers serialisers,
+    public RequestDeserializeHandler(Class<?> type, Type genericType, List<MediaType> acceptableMediaTypes,
+            ServerSerialisers serialisers,
             int parameterIndex) {
         this.type = type;
         this.genericType = genericType;
-        this.mediaType = mediaType;
+        this.acceptableMediaTypes = acceptableMediaTypes;
         this.serialisers = serialisers;
         this.parameterIndex = parameterIndex;
     }
 
     @Override
     public void handle(ResteasyReactiveRequestContext requestContext) throws Exception {
-        MediaType effectiveRequestType = mediaType;
-        String requestTypeString = requestContext.serverRequest().getRequestHeader(HttpHeaders.CONTENT_TYPE);
-        if (requestTypeString != null) {
+        MediaType effectiveRequestType = null;
+        Object requestType = requestContext.getHeader(HttpHeaders.CONTENT_TYPE, true);
+        if (requestType != null) {
             try {
-                effectiveRequestType = MediaType.valueOf(requestTypeString);
+                effectiveRequestType = MediaType.valueOf((String) requestType);
             } catch (Exception e) {
                 throw new WebApplicationException(Response.status(Response.Status.BAD_REQUEST).build());
             }
-        } else if (effectiveRequestType == null) {
+
+            // We need to verify media type for sub-resources, this mimics what is done in {@code ClassRoutingHandler}
+            if (MediaTypeHelper.getFirstMatch(
+                    acceptableMediaTypes,
+                    Collections.singletonList(effectiveRequestType)) == null) {
+                throw new NotSupportedException("The content-type header value did not match the value in @Consumes");
+            }
+        } else if (!acceptableMediaTypes.isEmpty()) {
+            effectiveRequestType = acceptableMediaTypes.get(0);
+        } else {
             effectiveRequestType = MediaType.APPLICATION_OCTET_STREAM_TYPE;
         }
         List<MessageBodyReader<?>> readers = serialisers.findReaders(null, type, effectiveRequestType, RuntimeType.SERVER);