diff --git a/.github/workflows/nightly-tests.yml b/.github/workflows/nightly-tests.yml
new file mode 100644
index 00000000..f478834e
--- /dev/null
+++ b/.github/workflows/nightly-tests.yml
@@ -0,0 +1,79 @@
+name: Run nightly tests
+
+on:
+  push:
+#  schedule:
+#    # For tests only: run every 15 minutes
+#    - cron: "*/15 * * * *"
+
+jobs:
+  run-unit-tests-2.3:
+    name: Unit tests - develop-2.3
+    runs-on: ubuntu-20.04
+
+    steps:
+      - name: Checkout develop-2.3
+        uses: actions/checkout@v3
+        with: { ref: develop-2.3 }
+
+      - name: Build the middleware docker image
+        run: docker/mware/build
+
+      - name: Middleware tests
+        run: middleware/test-all
+
+      - name: Ledger tests for TCPSigner
+        run: ledger/test/test-all
+
+      - name: Ledger Signer's tests
+        working-directory: ledger/src/signer/test/
+        run: |
+          for d in difficulty sha256 srlp; do
+            (cd "$d" && make clean test)
+          done
+
+      - name: Ledger common lib tests
+        working-directory: ledger/src/common/test/
+        run: |
+          for d in memutil; do
+            (cd "$d" && make clean test)
+          done
+
+  run-integration-tests-2.3:
+    name: Integration tests - develop2.3
+    runs-on: ubuntu-20.04
+
+    steps:
+      - name: Checkout rsk-powhsm repo
+        uses: actions/checkout@v2
+        with:
+          ref: develop-2.3
+          path: rsk-powhsm
+
+      - name: Build required software
+        working-directory: rsk-powhsm
+        run: |
+          docker/mware/build
+          docker/packer/build
+          middleware/build/manager-tcp
+          ledger/build/build-tcpsigner
+
+      - name: Checkout hsm-integration-test repo
+        uses: actions/checkout@v2
+        with:
+          repository: rootstock/hsm-integration-test
+          ref: 2.3.0.plus
+          path: hsm-integration-test
+          ssh-key: ${{ secrets.HSM_INTEGRATION_TEST_SSH_KEY }}
+
+      - name: Copy required files
+        run: |
+          mkdir hsm-integration-test/docker/manager/manager-tcp
+          tar -xzf rsk-powhsm/middleware/bin/manager-tcp.tgz \
+              -C hsm-integration-test/docker/manager/manager-tcp
+          cp rsk-powhsm/ledger/src/tcpsigner/tcpsigner \
+              hsm-integration-test/docker/tcpsigner/
+
+      - name: Run HSM integration tests
+        working-directory: hsm-integration-test
+        run: sh smoke-test.sh