diff --git a/bisect/35977.py b/bisect/35977.py
new file mode 100644
index 0000000000000..afdb86d607b79
--- /dev/null
+++ b/bisect/35977.py
@@ -0,0 +1,7 @@
+import pandas as pd
+
+print(pd.__version__)
+df = pd.DataFrame({"a": ["a", "b", "c"], "b": ["d", "", ""]}, dtype="string")
+
+df.replace(r"^\s*$", pd.NA, regex=True, inplace=True)
+print(df)