Global define applying too liberally

[meMuszr]

Describe the bug

Unable to use global in a string when building for production.

Reproduction

https://stackblitz.com/edit/vitejs-vite-oxtuwi?file=main.js

Steps to reproduce

View the correct output with npm run dev.
When running production build with npm run build; npm run preview; - notice that the C.GLOBAL_RED2 gets replaced with {}-red

System Info

Standard stackblitz instance -


  System:
    OS: Linux 5.0 undefined
    CPU: (8) x64 Intel(R) Core(TM) i9-9880H CPU @ 2.30GHz
    Memory: 0 Bytes / 0 Bytes
    Shell: 1.0 - /bin/jsh
  Binaries:
    Node: 16.14.2 - /usr/local/bin/node
    Yarn: 1.22.19 - /usr/local/bin/yarn
    npm: 7.17.0 - /usr/local/bin/npm
  npmPackages:
    vite: ^4.3.2 => 4.3.7 

### Used Package Manager

npm

### Logs

_No response_

### Validations

- [X] Follow our [Code of Conduct](https://github.com/vitejs/vite/blob/main/CODE_OF_CONDUCT.md)
- [X] Read the [Contributing Guidelines](https://github.com/vitejs/vite/blob/main/CONTRIBUTING.md).
- [X] Read the [docs](https://vitejs.dev/guide).
- [X] Check that there isn't [already an issue](https://github.com/vitejs/vite/issues) that reports the same bug to avoid creating a duplicate.
- [X] Make sure this is a Vite issue and not a framework-specific issue. For example, if it's a Vue SFC related bug, it should likely be reported to [vuejs/core](https://github.com/vuejs/core) instead.
- [X] Check that this is a concrete bug. For Q&A open a [GitHub Discussion](https://github.com/vitejs/vite/discussions) or join our [Discord Chat Server](https://chat.vitejs.dev/).
- [X] The provided reproduction is a [minimal reproducible example](https://stackoverflow.com/help/minimal-reproducible-example) of the bug.

[stackblitz]

Start a new pull request in StackBlitz Codeflow.

• vitejs-vite-oxtuwi (Open reproduction)

[sapphi-red]

You should not set global in define. See https://vitejs.dev/config/shared-options.html#define:~:text=Because%20it%27s%20implemented,or%20polyfilled%20instead.