Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

bwa-mem2 support to improve mapping speed #72

Closed
jianshu93 opened this issue May 19, 2021 · 1 comment
Closed

bwa-mem2 support to improve mapping speed #72

jianshu93 opened this issue May 19, 2021 · 1 comment

Comments

@jianshu93
Copy link

Dear Ben,
bwa-mem algorithm was improved and a 2x speedup is achieved. See here: https://ieeexplore.ieee.org/abstract/document/8820962?casa_token=KrlJpG5fVt8AAAAA:NUlxBO2400z4M-sFMCbDn2tSXTZj_y0si_MQgNbDvPd3y223cpV-si6b8DDWCWhl-1iSI3Gh

minimap2 is still not perfect for short reads mapping (https://lh3.github.io/2018/04/02/minimap2-and-the-future-of-bwa) but for large scale dataset the speed of minimap2 really fast. actually the syntax for bwa-mem2 is exactly the same with bwa. All need to add is to also recognize bwa-mem2 in the path, together with bwa and minimap2. I have done tests with bwa-mem2 and the output file and coverage are exactly the same with bwa but 2x speedup

Thanks,

Jianshu

@wwood
Copy link
Owner

wwood commented May 21, 2021

Good idea, thanks.

Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
None yet
Projects
None yet
Development

No branches or pull requests

2 participants