The models from various brain regions highlighted below have been well tested, with significant portions converted to NeuroML and/or PyNN.
See also Gleeson et al 2019.
Neocortex | Cerebellum | Hippocampus | Olfactory bulb | Invertebrate | General | Showcases | Others
| Model | Tests | Pull requests |
|---|---|---|
| Allen Institute Cell Types DB (Hawrylycz et al. 2016) Morphologically detailed and point neuron models based on electrophysiological recordings from visual cortex neurons |
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| Brunel (2000) Spiking network illustrating balance between excitation and inhibition |
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| Hay et al. (2011) Layer 5 pyramidal cell model constrained by somatic and dendritic recordings |
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| Izhikevich (2003) Spiking neuron model reproducing wide range of neuronal activity |
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| Markram et al. (2015) Cell models from Neocortical Microcircuit of Blue Brain Project |
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| Pospischil et al. (2008) HH based models for different classes of cortical and thalamic neurons |
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| Potjans and Diesmann (2014) Microcircuit model of sensory cortex with 8 populations across 4 layers |
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| Dura-Bernal et al. (2017) Model of mouse primary motor cortex (M1) |
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| Sadeh et al. (2017) Point neuron model of Inhibition Stabilized Network |
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| Smith et al. (2013) Layer 2/3 cell model used to investigate dendritic spikes |
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| Traub et al. (2005) Single column network model containing 14 cell populations from cortex and thalamus |
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| Bahl et al. (2012) A set of reduced models of layer 5 pyramidal neurons |
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| Wilson and Cowan (1972) A classic rate based model describing the dynamics and interactions between the excitatory and inhibitory populations of neurons |
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| del-Molino2017 Rate based model showing paradoxical response reversal of top-down modulation in cortical circuits with three interneuron types |
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| MejiasEtAl2016 A rate based model simulating the dynamics of a cortical laminar structure across multiple scales: intralaminar, interlaminar, interareal and whole cortex |
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| Model | Tests | Pull requests |
|---|---|---|
| Maex and De Schutter (1998) (GrC) Cerebellar granule cell |
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| Cayco-Gajic et al. (2017) Cerebellar granule cell layer network |
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| Maex and De Schutter (1998) 3D Cerebellar granule cell layer network |
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| Solinas et al. (2007) Cerebellar Golgi cell model |
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| Vervaeke et al. (2010) Electrically connected cerebellar Golgi cell network model |
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| Model | Tests | Pull requests |
|---|---|---|
| Bezaire et al. (2016) Full scale network model of CA1 region of hippocampus |
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| Ferguson et al. (2013) Parvalbumin-positive interneuron from CA1, based on Izhikevich cell model |
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| Ferguson et al. (2014) Pyramidal cell from CA1, based on Izhikevich cell model |
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| Migliore et al. (2005) Multicompartmental model of pyramidal cell from CA1 region of hippocampus |
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| Pinsky and Rinzel (1994) Simplified model of CA3 pyramidal cell |
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| Wang and Buzsaki (1996) Hippocampal interneuronal network model exhibiting gamma oscillations |
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| Model | Tests | Pull requests |
|---|---|---|
| Migliore et al. (2014) Large scale 3D olfactory bulb network with detailed mitral cells and granule cells |
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| Model | Tests | Pull requests |
|---|---|---|
| Hodgkin and Huxley (1952) Classic investigation of the ionic basis of the action potential |
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| FitzHugh (1961) Simplified form of Hodgkin Huxley model |
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| Prinz et al. (2004) Pyloric network of the lobster stomatogastric ganglion system |
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| Boyle and Cohen (2008) Model of body wall muscle from C. elegans |
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| Gleeson et al. (2018) A multiscale framework for modelling the nervous system of C. elegans |
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| Model | Tests | Pull requests |
|---|---|---|
| Morris and Lecar (1981) Two dimensional reduced neuron model with calcium and potassium conductances |
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| Hindmarsh and Rose (1984) A simplified point cell model which captures complex firing patterns of single neurons, such as periodic and chaotic bursting |
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| Model | Tests | Pull requests |
|---|---|---|
| NEST Showcase Examples of interactions with simulator NEST |
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| PyNN Showcase Examples of interactions between PyNN and NeuroML |
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| NetPyNE Showcase Examples of interactions between NeuroML and NetPyNE |
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| SBML Showcase Examples of interactions between NeuroML and SBML |
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| Brian Showcase Examples of interactions between NeuroML and Brian |
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| MOOSE Showcase Examples of interactions between NeuroML and MOOSE |
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| Arbor Showcase Examples of interactions between NeuroML and Arbor |
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| EDEN Showcase Examples of interactions between NeuroML and EDEN |
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| The Virtual Brain Showcase Examples of interactions between NeuroML and TVB |
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| NEURON Showcase Examples of interactions between NeuroML and NEURON |
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| neuroConstruct Showcase Examples of neuroConstruct projects |
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| NeuroMorpho.Org Examples of reconstructions from NeuroMorpho.Org |
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| Janelia MouseLight Janelia MouseLight project neuronal reconstructions |
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| NSGPortalShowcase Interactions with Neuroscience Gateway |
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Note: these models may still be in development, or may not have been recently updated. Use with caution.
