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dcos #32

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Nov 25, 2021
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docs
ypriverol Nov 25, 2021
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Merge remote-tracking branch 'origin/dev' into dev
ypriverol Nov 25, 2021
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6 changes: 4 additions & 2 deletions docs/identification.rst
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Expand Up @@ -6,7 +6,8 @@ The peptide/protein identification workflow is the cornerstone of the Data depen
In DDA mode, the mass spectrometer first records the mass/charge (m/z) of each peptide ion and then selects the peptide ions individually to obtain sequence information via MS/MS (Figure 1). As a result for each sample, millions of MS and corresponding MS/MS are obtained which correspond to all peptides in the mixture.

.. image:: images/msms.png
:width: 350
:width: 600
:align: center

In order to identified the MS/MS spectra, several computational algorithms and tools can now be used to identify peptides and proteins. The most popular ones are based on protein sequence databases, where the experimental MS/MS is compared with the theoretical MS/MS of each peptide obtained from the insilico digestion of the protein database [read review ref 1].

Expand All @@ -21,7 +22,8 @@ However, most of the computational proteomics tools are designed as single-tiere
- creation of reports

.. image:: images/id-dda-pipeline.png
:width: 350
:width: 400
:align: center

Mass spectra processing: Raw conversion
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3 changes: 2 additions & 1 deletion docs/introduction.rst
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Expand Up @@ -5,7 +5,8 @@ Bottom-up proteomics is a common method to identify proteins and characterize th


.. image:: images/ms-proteomics.png
:width: 350
:width: 400
:align: center


.. sidebar:: Pipelines and tools
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