First binary contribution with OS autodetection.

Python.Config.dll - is an all in one binary distribution of PythonNet.
It supports Win64,Linux64, Python 2.7, Python 3.5

pcfgtest.exe is a diagnostic utility.

If you put bootstrap code:

        static Program()
        {
            Console.WriteLine("Starting application...");
            // Required to be placed in the static constructor for Mono.
            PythonConfig.EnsureInitialized();
        }

        [STAThread]
        private static int Main(string[] args)
        {
            // Mono workaround required to fix AssemblyResolve + EntryPoint class bug.
            // Classes that was referenced from EntryPoint class cannot use assemblies resolved through "AssemblyResolve"
            Action monoWorkaround = () =>
                {
                    try
                    {
                        // You should put this initialized only if some component starting to use it before first application configuration file read attempt.
                        // So in rare cases.
                        PythonEngine.Initialize();

to your project and switch off "copy local" property on Python.Runtime.dll assembly, then different version of Python.Runtime.dll will be loaded.
You also should put version into configuration file:

<?xml version="1.0" encoding="utf-8" ?>
<configuration>
  <configSections>
    <section name="pythonConfig" type="Python.Config.PythonConfigSection, Python.Config, Version=1.0.0.0, Culture=neutral, PublicKeyToken=null"/>
  </configSections>
  <pythonConfig pythonVersion="3.5"/>
</configuration>