Skip to content
New issue

Have a question about this project? Sign up for a free GitHub account to open an issue and contact its maintainers and the community.

By clicking “Sign up for GitHub”, you agree to our terms of service and privacy statement. We’ll occasionally send you account related emails.

Already on GitHub? Sign in to your account

Fix cell soup in center of late development epithelium #27

Open
lavinrp opened this issue Jul 21, 2019 · 1 comment
Open

Fix cell soup in center of late development epithelium #27

lavinrp opened this issue Jul 21, 2019 · 1 comment
Labels
bug Something isn't working question Further information is requested

Comments

@lavinrp
Copy link
Owner

lavinrp commented Jul 21, 2019

image

This is from a 10000 cell epithelium generated with default settings and run with default settings.
Everything seems fine until cells start to die.

image

@lavinrp
Copy link
Owner Author

lavinrp commented Jul 21, 2019

This seems to be caused by cells continuing to grow after specialization. This causes LOTS of collision issues in the center of the epithelium where its not easy for cells to find a empty space. Eventually the Support cells start to wedge themselves into the ommatidium.

@shubhamTR
There are a LOT of variables at play to produce this.

  1. Cell Adhesion values may not be optimal.
    • If R* cells had stronger adhesion to each other than to support cells that may help the issue
  2. Cell growth rate may not be optimal
    • The cells are growing quickly causing them to push into each other. A slower (or zero) growth rate of specialized cells may alleviate this.
      • Specialized is bold b/c the growth of the unspecialized cells doesn't really impact this much right now
  3. Cells may be allowed to grow too big
    • By default tehse cells won't divide until they are 2.5 times the size they start at. This causes a lot of pushing.
  4. Internal cell collision logic may not be good enough.

@lavinrp lavinrp added bug Something isn't working question Further information is requested labels Jul 21, 2019
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment
Labels
bug Something isn't working question Further information is requested
Projects
None yet
Development

No branches or pull requests

1 participant