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Treatment with any member of a group of drugs that reduce the activity of 4-hydroxyphenylpyruvate dioxygenase. An example is NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione).
Comment: In patients with tyrosinemia, treatment with NTBC has been shown to efficiently prevent tyrosine degradation, and production of succinylacetone.PMID: 9728331
The text was updated successfully, but these errors were encountered:
@LCCarmody
We need this for the Tyrosinaemia type I example
see - https://pubmed.ncbi.nlm.nih.gov/9728331/ and other OMIM entries
suggested def
Treatment with any member of a group of drugs that reduce the activity of 4-hydroxyphenylpyruvate dioxygenase. An example is NTBC (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione).
Comment: In patients with tyrosinemia, treatment with NTBC has been shown to efficiently prevent tyrosine degradation, and production of succinylacetone.PMID: 9728331
The text was updated successfully, but these errors were encountered: