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Open Targets and PharmaProjects gene indication pairs
Filename: OpenTargets_Pprojects_drugs_TTlabel.csv
Number of rows (including header): 8,183
This data set is subject to the following terms and conditions. By downloading these data from this site, you agree to these terms.
Informa Business Intelligence, Inc. (Informa) grants you a limited, revocable, non-exclusive, non-transferable right to use the Pharmaprojects data and information being made available for download (Informa Data) solely to the minimum extent necessary for your participation in the BioData West Open Targets Datathon taking place in San Francisco, CA on March 12, 2018. You will not acquire any ownership or intellectual property rights in the Informa Data, all of which belong to Informa. You may not share the Informa Data with any persons other than other participants of the Workshop. The Informa Data is provided “AS IS” without warrant of any kind. Informa is not liable to you or any third party for any adverse consequences arising as a result of the inaccuracy or incompleteness of the Informa Data. Informa will not be liable to you or any third party for any trading, investment, commercial or other decisions based on or made in reliance on the Informa Data. You will, no later than five (5) days after conclusion of the Workshop, permanently delete and destroy all copies of the Informa Data within your possession or control. It is understood and agreed that the Informa Data is being provided to you on a complimentary basis. As such, the total liability of Informa to you with respect to the Informa Data shall not exceed $10.
Filename: Pprojects_drugs_TTlabel.csv
This data set is subject to the following terms and conditions. By downloading these data from this site, you agree to these terms.
Informa Business Intelligence, Inc. (Informa) grants you a limited, revocable, non-exclusive, non-transferable right to use the Pharmaprojects data and information being made available for download (Informa Data) solely to the minimum extent necessary for your participation in the BioData West Open Targets Datathon taking place in San Francisco, CA on March 12, 2018. You will not acquire any ownership or intellectual property rights in the Informa Data, all of which belong to Informa. You may not share the Informa Data with any persons other than other participants of the Workshop. The Informa Data is provided “AS IS” without warrant of any kind. Informa is not liable to you or any third party for any adverse consequences arising as a result of the inaccuracy or incompleteness of the Informa Data. Informa will not be liable to you or any third party for any trading, investment, commercial or other decisions based on or made in reliance on the Informa Data. You will, no later than five (5) days after conclusion of the Workshop, permanently delete and destroy all copies of the Informa Data within your possession or control. It is understood and agreed that the Informa Data is being provided to you on a complimentary basis. As such, the total liability of Informa to you with respect to the Informa Data shall not exceed $10.
Number of rows (including header): 14,549
Note this data is interpreted from Pharmaprojects XML output (as of 5Aug2017) and cannot be kept in any form beyond the period of this workshop. Errors in interpretation may have occurred.
| Column name | Description |
|---|---|
| target_indication | Target indication pair |
| ensembl_gene_id | target identifier (ENSEMBL) |
| disease_id | disease identifier (EFO) |
| entrez_id | target identifier (EntrezGene) |
| MeSH_ID | disease identifier (Medical Subject Heading) |
| Disease Type | Neoplasm (cancer) or Non-Neoplasm |
| Clinical Label_PP (Succeeded; Clinical Failure; In Progress Clinical) | Indicates the best reported outcome for any asset for this target-indication pair |
| Furthest Phase | Indicates the furthest reported phase for any asset for this target-indication pair. This includes assets reported as In Progress Clinical |
| Therapeutic Direction (Activator; Inhibitor; Mixed/Unknown) | Indicates the collective nature of the assets if >90% are in the same direction |
| Indication with First Clinical Outcome of Target (Y;N) | Indicates whether the indication was the first one with a reported clinical outcome for the indicated target |
| Types of Assets (Selective; Non-Selective) | Indicated whether the assets are reported by Pharamaprojects to be against a single target or multiple targets |
| Suggested Dataset Utility (Training; Test; Neither) | For those TIP pairs reported as First Clinical Outcomes, we have chosen ~80% of these as "Training" and 20% as "Test", doing our best to balance the indications attempted by each. Note that outcome data is very highly correlated (similar diseases are subsequently attempted with assets against a successfully treated disease), and so typical cross-validation schemes are not useful |