An online resource for exploring drug-induced QT interval prolongation
Available at www.deltaqt.org
This project contains all the source code for creating ∆QT Database (∆QTDb) and running the web application. We built the ∆QTDb web app using React and D3 for the frontend (see qtdb.html) and Bottle for the backend (see application.py; also requires PyMySQL).
We created ∆QTDb by deidentifying a subset of electronic health recored (EHR) data mapped to the Observational Health Data Sciences and Informatics Common Data Model (OHDSI CDM), https://www.ohdsi.org/. See http://www.deltaqt.org/faq#data-processing for a description of the deidentification protocol.
The Python script for creating the database (see create_QTDb.py) has been tested on OHDSI CDM v4 and v5. Running the script requires:
After running the database creation script, see create_QTDb_tables.sql for the MySQL queries to create and load the database.
We will update this README with citation information once the associated manuscript has been published. For questions about ∆QTDb contact:
Tal Lorberbaum: tal.lorberbaum_columbia.edu
Nicholas Tatonetti: nick.tatonetti_columbia.edu
∆QT Database is released under a Creative Commons BY-NC-SA 4.0 license. For complete details see LICENSE.txt or visit http://creativecommons.org/licenses/by-nc-sa/4.0/
