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Fixes #2732 ntr cxg atretic theca cell #2733

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merged 3 commits into from
Nov 7, 2024
Merged

Fixes #2732 ntr cxg atretic theca cell #2733

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f918218
Fixes #2732
Caroline-99 Nov 6, 2024
eba7eb2
Update cl-edit.owl
Caroline-99 Nov 6, 2024
c053166
updated the definition
Caroline-99 Nov 6, 2024
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12 changes: 12 additions & 0 deletions src/ontology/cl-edit.owl
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Original file line number Diff line number Diff line change
Expand Up @@ -3122,6 +3122,7 @@ Declaration(Class(obo:CL_4052022))
Declaration(Class(obo:CL_4052023))
Declaration(Class(obo:CL_4052024))
Declaration(Class(obo:CL_4052025))
Declaration(Class(obo:CL_4052027))
Declaration(Class(obo:CL_4052048))
Declaration(Class(obo:CL_4052049))
Declaration(Class(obo:CP_0000000))
Expand All @@ -3134,6 +3135,7 @@ Declaration(Class(obo:CP_0000039))
Declaration(Class(obo:CP_0000040))
Declaration(Class(obo:CP_0000043))
Declaration(Class(obo:D96882F1-8709-49AB-BCA9-772A67EA6C33))
Declaration(Class(obo:GO_0001552))
Declaration(Class(obo:GO_0005903))
Declaration(Class(obo:GO_0005927))
Declaration(Class(obo:GO_0031045))
Expand Down Expand Up @@ -33123,6 +33125,16 @@ AnnotationAssertion(Annotation(oboInOwl:hasSynonymType obo:OMO_0003000) oboInOwl
AnnotationAssertion(rdfs:label obo:CL_4052025 "neuromuscular junction nucleus")
EquivalentClasses(obo:CL_4052025 ObjectIntersectionOf(obo:GO_0005634 ObjectSomeValuesFrom(obo:BFO_0000050 obo:CL_0008046) ObjectSomeValuesFrom(obo:RO_0002131 obo:GO_0098522)))

# Class: obo:CL_4052027 (atretic theca cell)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:20628033") Annotation(oboInOwl:hasDbXref "PMID:38069168") obo:IAO_0000115 obo:CL_4052027 "A theca cell undergoing atresia, characterized by distinct morphological changes including hypertrophy, altered cell shape, and disrupted layered organization. This cell exhibits reduced steroidogenic capacity and changes in surrounding vascularization. The onset of theca cell atresia can vary, occurring at different stages of follicle atresia depending on the phase of folliculogenesis.")
AnnotationAssertion(terms:contributor obo:CL_4052027 <https://orcid.org/0009-0000-8480-9277>)
AnnotationAssertion(terms:date obo:CL_4052027 "2024-11-06T10:10:51Z"^^xsd:dateTime)
AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:38069168") rdfs:comment obo:CL_4052027 "During atresia, theca interna and externa cells undergo distinct morphological and functional changes. Theca interna cells round up, expand in cytoplasmic area, and thicken the internal layer as organization degrades, while showing reduced STAR expression, which lowers androgen production. Theca externa cells display decreased ACTA2 expression, weakening structural integrity.")
AnnotationAssertion(rdfs:label obo:CL_4052027 "atretic theca cell")
SubClassOf(obo:CL_4052027 obo:CL_4033089)
SubClassOf(obo:CL_4052027 ObjectSomeValuesFrom(obo:RO_0002202 obo:CL_0000503))

# Class: obo:CL_4052048 (intercalated cell of salivary gland)

AnnotationAssertion(Annotation(oboInOwl:hasDbXref "PMID:30855909") Annotation(oboInOwl:hasDbXref "PMID:35799078") Annotation(oboInOwl:hasDbXref "PMID:36726292") Annotation(oboInOwl:hasDbXref "PMID:37724716") obo:IAO_0000115 obo:CL_4052048 "A cuboidal epithelial cell that is part of the intercalated duct of salivary gland. This cell expresses proteins commonly associated with acinar cells and displays calcium signaling characteristics similar to secretory cells, indicating an active role in the secretory process rather than ion reabsorption.")
Expand Down
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